First-line durvalumab therapy alone or in combination with tremelimumab for metastatic head and neck squamous cell carcinoma: A cost-effectiveness analysis

Huijuan Li; Xueyan Liang; Shiran Qin; Xiaoyu Chen; Liju Huang; Yan Li

doi:10.1371/journal.pone.0324057

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Open Access

Peer-reviewed

Research Article

First-line durvalumab therapy alone or in combination with tremelimumab for metastatic head and neck squamous cell carcinoma: A cost-effectiveness analysis

Huijuan Li ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

¶☯ Huijuan Li and Xueyan Liang contributed equally to this study.

Affiliations Drug Clinical Trial Institution, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China, Phase I Clinical Trial Laboratory, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China, Department of Pharmacy, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China
⨯
Xueyan Liang ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft

¶☯ Huijuan Li and Xueyan Liang contributed equally to this study.

Affiliation Phase I Clinical Trial Laboratory, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China
⨯
Shiran Qin,

Roles Data curation, Formal analysis

Affiliation Department of Pharmacy, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China
⨯
Xiaoyu Chen,

Roles Investigation, Resources, Supervision, Validation, Visualization

Affiliations Phase I Clinical Trial Laboratory, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China, Department of Pharmacy, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China
⨯
Liju Huang ,

Roles Conceptualization, Formal analysis, Investigation, Project administration, Resources, Supervision, Visualization, Writing – review & editing

* E-mail: yli@gxams.org.cn (YL); 395154496@qq.com (LH)

Affiliation Phase I Clinical Trial Laboratory, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China
⨯
Yan Li

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Validation, Writing – review & editing

* E-mail: yli@gxams.org.cn (YL); 395154496@qq.com (LH)

Affiliation Department of Pharmacy, Guangxi Academy of Medical Sciences and the People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, People’s Republic of China

https://orcid.org/0009-0003-3520-8880

⨯

First-line durvalumab therapy alone or in combination with tremelimumab for metastatic head and neck squamous cell carcinoma: A cost-effectiveness analysis

Huijuan Li,
Xueyan Liang,
Shiran Qin,
Xiaoyu Chen,
Liju Huang,
Yan Li

Published: May 16, 2025
https://doi.org/10.1371/journal.pone.0324057

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Cancer treatment
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Head and neck squamous cell carcinoma
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