Whole genome sequencing revealed esophageal squamous cell carcinoma related biomarkers

Mingjun Li; Lei Li; Xizi Wang; Yanwei Zhao; Peina Du; Wei Wang; Zhenxing Wang; Yadong Wang; Yanxing Sheng; Mingliang Gu; Xiaodong Jia

doi:10.1371/journal.pone.0323915

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Open Access

Peer-reviewed

Research Article

Whole genome sequencing revealed esophageal squamous cell carcinoma related biomarkers

Mingjun Li ,

Contributed equally to this work with: Mingjun Li, Lei Li, Xizi Wang

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Radiotherapy, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Lei Li ,

Contributed equally to this work with: Mingjun Li, Lei Li, Xizi Wang

Roles Formal analysis, Methodology, Software, Writing – original draft

Affiliations BGI Research, Shenzhen, China, BGI Research, Qingdao, China
⨯
Xizi Wang ,

Contributed equally to this work with: Mingjun Li, Lei Li, Xizi Wang

Roles Formal analysis, Software, Writing – original draft

Affiliation Joint Laboratory for Translational Medicine Research, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Yanwei Zhao,

Roles Data curation, Investigation

Affiliation Department of Radiotherapy, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Peina Du,

Roles Formal analysis

Affiliations BGI Genomics, Shenzhen, China, Clin Lab, BGI Genomics, Qingdao, China
⨯
Wei Wang,

Roles Investigation

Affiliation Department of Thoracic Surgery, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Zhenxing Wang,

Roles Investigation

Affiliation Department of Thoracic Surgery, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Yadong Wang,

Roles Investigation

Affiliation Department of Thoracic Surgery, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Yanxing Sheng,

Roles Methodology, Supervision

Affiliation Department of Radiotherapy, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Mingliang Gu,

Roles Project administration, Supervision

Affiliation Joint Laboratory for Translational Medicine Research, Liaocheng People’s Hospital, Liaocheng, Shandong, China
⨯
Xiaodong Jia

Roles Conceptualization, Data curation, Methodology, Supervision, Writing – review & editing

* E-mail: jiaxiaodong1018@163.com

Affiliation Joint Laboratory for Translational Medicine Research, Liaocheng People’s Hospital, Liaocheng, Shandong, China

https://orcid.org/0000-0002-1901-1442

⨯

Whole genome sequencing revealed esophageal squamous cell carcinoma related biomarkers

Mingjun Li,
Lei Li,
Xizi Wang,
Yanwei Zhao,
Peina Du,
Wei Wang,
Zhenxing Wang,
Yadong Wang,
Yanxing Sheng,
Mingliang Gu

Published: June 26, 2025
https://doi.org/10.1371/journal.pone.0323915

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Squamous cell carcinoma
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Somatic mutation
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Nonsense mutation
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Malignant tumors
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Oncogenes
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Esophageal cancer
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Cancers and neoplasms
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Mutation detection
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