Network pharmacology and experimental validation to investigate the mechanism of action of Zhilong Huoxue Tongyu capsule in the prevention and treatment of diabetic cardiomyopathy

• Fang Yang ,

  Contributed equally to this work with: Fang Yang, Gang Luo

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Gang Luo ,

  Contributed equally to this work with: Fang Yang, Gang Luo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Meng-nan Liu,

  Roles Data curation, Investigation, Methodology, Project administration, Resources, Software, Supervision

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Ping Liu,

  Roles Project administration, Resources, Software, Validation

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Dan Wu,

  Roles Data curation, Formal analysis, Software, Validation

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Hao-ling Chen,

  Roles Conceptualization, Data curation, Software, Validation

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Shan Li,

  Roles Investigation, Methodology, Software

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Si-Jin Yang ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: xiaodongluyi@126.com (LD); ysjimn@sina.com (SY)

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

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• Li Dong

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: xiaodongluyi@126.com (LD); ysjimn@sina.com (SY)

  Affiliations National Traditional Chinese Medicine Clinical Research Base and Cardiology department of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China, Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, China

  https://orcid.org/0009-0003-0320-9045

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