β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice

Jainu Ajit; Qing Chen; Trevor Ung; Matthew Rosenberger; Jeremiah Kim; Ani Solanki; Jingjing Shen; Aaron P. Esser Kahn

doi:10.1371/journal.pone.0323376

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Open Access

Peer-reviewed

Research Article

β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice

Jainu Ajit,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Qing Chen,

Roles Investigation, Validation

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Trevor Ung,

Roles Investigation, Validation

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Matthew Rosenberger,

Roles Investigation, Validation

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Jeremiah Kim,

Roles Investigation, Validation

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Ani Solanki,

Roles Investigation, Validation

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Jingjing Shen,

Roles Investigation, Validation

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America
⨯
Aaron P. Esser Kahn

Roles Conceptualization, Funding acquisition, Project administration, Resources, Software, Supervision, Writing – review & editing

* E-mail: aesserkahn@uchicago.edu

Affiliation Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, United States of America

https://orcid.org/0000-0003-1273-0951

⨯

β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice

Jainu Ajit,
Qing Chen,
Trevor Ung,
Matthew Rosenberger,
Jeremiah Kim,
Ani Solanki,
Jingjing Shen,
Aaron P. Esser Kahn

Published: May 22, 2025
https://doi.org/10.1371/journal.pone.0323376

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Antibodies
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