Itaconate potentiates hepatic gluconeogenesis through NRF2 induction

• Marwa O. El-Derany,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt

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• Sadeesh K. Ramakrishnan,

  Roles Data curation, Methodology, Writing – original draft

  present at Department of medicine, University of Pittsburgh

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Yingjie Li,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Kathryn Buscher,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Christina A. Jarad,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Megan L. Schaller,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Marc Cantwell,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Thomas M. Vigil,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Ryan A. Frieler,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Peter Sajjakulnukit,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, United States of America

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• Costas A. Lyssiotis,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America, University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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• Richard M. Mortensen,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Yatrik M. Shah

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: shahy@umich.edu

  Affiliations Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America, University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-2487-4816

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