Simulation study to evaluate when Plasmode simulation is superior to parametric simulation in comparing classification methods on high-dimensional data

Marieke Stolte; Nicholas Schreck; Alla Slynko; Maral Saadati; Axel Benner; Jörg Rahnenführer; Andrea Bommert; for the topic group “High-dimensional data” (TG9) of the STRATOS Initiative

doi:10.1371/journal.pone.0322887

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Open Access

Peer-reviewed

Research Article

Simulation study to evaluate when Plasmode simulation is superior to parametric simulation in comparing classification methods on high-dimensional data

Marieke Stolte ,

Roles Conceptualization, Formal analysis, Software, Visualization, Writing – original draft

* E-mail: stolte@statistik.tu-dortmund.de

Affiliation Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany

https://orcid.org/0009-0002-0711-6789

⨯
Nicholas Schreck,

Roles Conceptualization, Writing – review & editing

Affiliations Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany, Faculty of Liberal Arts and Sciences, Technical University of Applied Sciences Augsburg, Augsburg, Bavaria, Germany
⨯
Alla Slynko,

Roles Conceptualization, Writing – review & editing

Affiliation Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada
⨯
Maral Saadati,

Roles Conceptualization, Writing – review & editing

Affiliation Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany
⨯
Axel Benner,

Roles Conceptualization, Writing – review & editing

Affiliation Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany
⨯
Jörg Rahnenführer,

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany
⨯
Andrea Bommert,

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

Affiliation Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany
⨯
for the topic group “High-dimensional data” (TG9) of the STRATOS Initiative

¶‡ Membership of the topic group “High-dimensional data” (TG9) of the STRATOS initiative is provided inthe Acknowledgments.
⨯

Simulation study to evaluate when Plasmode simulation is superior to parametric simulation in comparing classification methods on high-dimensional data

Marieke Stolte,
Nicholas Schreck,
Alla Slynko,
Maral Saadati,
Axel Benner,
Jörg Rahnenführer,
Andrea Bommert,
for the topic group “High-dimensional data” (TG9) of the STRATOS Initiative

Published: June 2, 2025
https://doi.org/10.1371/journal.pone.0322887

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