Protocol: Filgotinib in addition to methotrexate versus filgotinib monotherapy in patients with rheumatoid arthritis with an inadequate response to methotrexate: A multicenter, prospective, open-label, randomized controlled trial (FAITHFUL Study)

• Mitsuhiro Akiyama,

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

  https://orcid.org/0000-0001-5075-8977

  ⨯
• Toshihiko Hidaka,

  Roles Investigation, Writing – review & editing

  Affiliation Institute of Rheumatology, Miyazaki Zenjinkai Hospital, Miyazaki, Japan

  ⨯
• Motohide Kaneko,

  Roles Investigation, Writing – review & editing

  Affiliation Kaneko Internal Medicine Rheumatology Clinic, Kawaguchi, Japan

  ⨯
• Satoshi Ito,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Rheumatology, Niigata Rheumatic Center, Shibata, Japan

  ⨯
• Hiroaki Taguchi,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine and Center for Arthritis and Rheumatic Disease, Kawasaki Municipal Kawasaki Hospital, Kawasaki, Japan

  ⨯
• Tomonori Ishii,

  Roles Investigation, Writing – review & editing

  Affiliation Tohoku Medical and Pharmaceutical University, Division of Hematology and Rheumatology, Sendai, Japan

  https://orcid.org/0000-0001-5361-5824

  ⨯
• Shuji Asai,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

  ⨯
• Shintaro Hirata,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan

  ⨯
• Kei Ikeda,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Rheumatology, Dokkyo Medical University, Mibu, Japan

  ⨯
• Katsuya Suzuki,

  Roles Investigation, Writing – review & editing

  Affiliation Division of Rheumatology, Department of Internal Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan

  ⨯
• Naoki Kato,

  Roles Methodology, Writing – review & editing

  Affiliation Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation, Kobe, Japan

  ⨯
• Yuko Kaneko

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: ykaneko.z6@keio.jp

  Affiliation Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

  ⨯