Unleashing the anti-tumor angiogenic potential of nano-formulated orientin: In Silico, In Vitro, and In Ovo studies

• Yashwanth Elumalai,

  Roles Investigation

  Affiliation Faculty of Allied Health Science, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India

  https://orcid.org/0009-0004-8861-0643

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• Kathiresan Nachammai,

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India

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• Kirubhanand Chandrasekaran ,

  Roles Formal analysis, Investigation

  ¶‡ These authors share first authorship on this work.

  Affiliation Department of Anatomy, AIIMS, Nagpur, India

  ⨯
• Langeswaran Kulanthaivel,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India

  ⨯
• Sharon Benita Stephen ,

  Roles Methodology, Project administration

  ¶‡ These authors share first authorship on this work.

  Affiliation Faculty of Allied Health Science, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India

  ⨯
• Kanu Shil ,

  Roles Data curation

  ¶‡ These authors share first authorship on this work.

  Affiliation Faculty of Paramedical Sciences, Assam Down town University, Guwahati, Assam, India

  ⨯
• Ram Kumar Anandan,

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India

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• Abdulhadi Ibrahim Bima,

  Roles Formal analysis, Validation

  Affiliation Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

  ⨯
• Zeenath Khan,

  Roles Formal analysis, Investigation

  Affiliation Department of Science, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia

  ⨯
• Abdulhadi S. Burzangi,

  Roles Formal analysis, Investigation

  Affiliation Department of Clinical Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

  ⨯
• Noor A. Shaik,

  Roles Formal analysis, Investigation

  Affiliation Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

  ⨯
• Nuha Al-Rayes ,

  Roles Supervision, Visualization

  * E-mail: gowtham_phd@yahoo.com (GKS), nalrayes@kau.edu.sa (NA)

  Affiliations Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Addulaziz University, Jeddah, Saudi Arabia, Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia

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• Gowtham Kumar Subbaraj

  Roles Investigation, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: gowtham_phd@yahoo.com (GKS), nalrayes@kau.edu.sa (NA)

  Affiliation Faculty of Allied Health Science, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamil Nadu, India

  https://orcid.org/0000-0002-0531-424X

  ⨯