Analysis of Na+ concentration patterns in trophectoderm cells of mouse blastocysts using a dual-wavelength electrolyte indicator

Ayaka Fujishima; Kazumasa Takahashi; Mayumi Goto; Akiko Fujishima; Takeo Hirakawa; Takuya Iwasawa; Hiromitsu Shirasawa; Yukiyo Kumazawa; Yukihiro Terada

doi:10.1371/journal.pone.0322286

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Open Access

Peer-reviewed

Research Article

Analysis of Na⁺ concentration patterns in trophectoderm cells of mouse blastocysts using a dual-wavelength electrolyte indicator

Ayaka Fujishima ,

Roles Data curation, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

* E-mail: fujishimaayaka@med.akita-u.ac.jp

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan

https://orcid.org/0009-0001-7138-086X

⨯
Kazumasa Takahashi,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Mayumi Goto,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Akiko Fujishima,

Roles Conceptualization, Resources, Supervision

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Takeo Hirakawa,

Roles Formal analysis, Validation, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Takuya Iwasawa,

Roles Supervision, Validation

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Hiromitsu Shirasawa,

Roles Formal analysis, Supervision, Validation

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Yukiyo Kumazawa,

Roles Funding acquisition, Supervision, Validation

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯
Yukihiro Terada

Roles Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, Akita University Graduate School of Medicine, Akita, Japan
⨯

Analysis of Na⁺ concentration patterns in trophectoderm cells of mouse blastocysts using a dual-wavelength electrolyte indicator

Ayaka Fujishima,
Kazumasa Takahashi,
Mayumi Goto,
Akiko Fujishima,
Takeo Hirakawa,
Takuya Iwasawa,
Hiromitsu Shirasawa,
Yukiyo Kumazawa,
Yukihiro Terada

Published: April 30, 2025
https://doi.org/10.1371/journal.pone.0322286

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Electrolytes
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