Zebrafish Polymerase Theta and human Polymerase Theta: Orthologues with homologous function

Corey Thomas; Sydney Green; Lily Kimball; Isaiah R. Schmidtke; Lauren Rothwell; Makayla Griffin; Ivy Par; Sophia Schobel; Yayleene Palacio; Jamie B. Towle-Weicksel; Steven E. Weicksel

doi:10.1371/journal.pone.0321886

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Open Access

Peer-reviewed

Research Article

Zebrafish Polymerase Theta and human Polymerase Theta: Orthologues with homologous function

Corey Thomas,

Roles Investigation

Affiliation Department of Physical Sciences, Rhode Island College, Providence, Rhode Island, United States of America
⨯
Sydney Green,

Roles Investigation

Affiliation Department of Physical Sciences, Rhode Island College, Providence, Rhode Island, United States of America
⨯
Lily Kimball,

Roles Investigation

Affiliation Department of Biology and Biological Sciences, Bryant University, Smithfield, Rhode Island, United States of America
⨯
Isaiah R. Schmidtke,

Roles Investigation

Affiliation Department of Biology and Biological Sciences, Bryant University, Smithfield, Rhode Island, United States of America
⨯
Lauren Rothwell,

Roles Investigation

Affiliation Department of Biology and Biological Sciences, Bryant University, Smithfield, Rhode Island, United States of America
⨯
Makayla Griffin,

Roles Investigation

Affiliation Department of Biology and Biological Sciences, Bryant University, Smithfield, Rhode Island, United States of America
⨯
Ivy Par,

Roles Investigation

Affiliation Department of Physical Sciences, Rhode Island College, Providence, Rhode Island, United States of America
⨯
Sophia Schobel,

Roles Investigation

Affiliation Department of Physical Sciences, Rhode Island College, Providence, Rhode Island, United States of America
⨯
Yayleene Palacio,

Roles Investigation

Affiliation Department of Physical Sciences, Rhode Island College, Providence, Rhode Island, United States of America
⨯
Jamie B. Towle-Weicksel,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Physical Sciences, Rhode Island College, Providence, Rhode Island, United States of America
⨯
Steven E. Weicksel

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

* E-mail: sweicksel@bryant.edu

Affiliation Department of Biology and Biological Sciences, Bryant University, Smithfield, Rhode Island, United States of America

https://orcid.org/0000-0002-1679-9684

⨯

Zebrafish Polymerase Theta and human Polymerase Theta: Orthologues with homologous function

Corey Thomas,
Sydney Green,
Lily Kimball,
Isaiah R. Schmidtke,
Lauren Rothwell,
Makayla Griffin,
Ivy Par,
Sophia Schobel,
Yayleene Palacio,
Jamie B. Towle-Weicksel

Published: April 29, 2025
https://doi.org/10.1371/journal.pone.0321886

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Nucleotides
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DNA polymerase
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Zebrafish
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Polymerases
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DNA damage
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Microhomology-mediated end joining
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DNA repair
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Magnesium chloride
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