In silico analysis to explore the therapeutic potential of propolis-derived small molecules as matriptase inhibitors to suppress breast cancer growth and metastasis

• Muhammad Bilal Azmi ,

  Contributed equally to this work with: Muhammad Bilal Azmi, Han Yu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Writing – review & editing

  * E-mail: bilal.azmi@duhs.edu.pk (MBA); mohnadabdalla200@gmail.com (MA)

  Affiliation Computational Biochemistry Research Laboratory, Department of Biochemistry, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

  https://orcid.org/0000-0001-8320-4479

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• Han Yu ,

  Contributed equally to this work with: Muhammad Bilal Azmi, Han Yu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

  Affiliations Children’s Hospital Affiliated to Shandong University, Jinan, China, Jinan Children’s Hospital, Jinan, China, Department of Computational Biology, School of Life Sciences, Fudan University, Shanghai, China

  https://orcid.org/0000-0002-4229-0806

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• Arisha Sohail,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Writing – original draft

  Affiliation Computational Biochemistry Research Laboratory, Department of Biochemistry, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

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• Uzma Asif,

  Roles Formal analysis, Funding acquisition, Investigation, Software, Visualization, Writing – original draft

  Affiliation Department of Biochemistry, Medicine Program, Batterjee Medical College, Jeddah, Saudi Arabia

  https://orcid.org/0000-0002-4659-9173

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• Syed Danish Haseen Ahmed,

  Roles Data curation, Formal analysis, Funding acquisition, Supervision, Validation, Writing – review & editing

  Affiliation Computational Biochemistry Research Laboratory, Department of Biochemistry, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

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• Shamim Akhtar Qureshi,

  Roles Data curation, Funding acquisition, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Department of Biochemistry, University of Karachi, Karachi, Pakistan

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• Mohnad Abdalla

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Visualization, Writing – review & editing

  * E-mail: bilal.azmi@duhs.edu.pk (MBA); mohnadabdalla200@gmail.com (MA)

  Affiliations Children’s Hospital Affiliated to Shandong University, Jinan, China, Jinan Children’s Hospital, Jinan, China

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