Functional kinome profiling reveals brain protein kinase signaling pathways and gene networks altered by acute voluntary exercise in rats

• Chia-Ming Lee ,

  Contributed equally to this work with: Chia-Ming Lee, Jennifer Nguyen

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Physiology and Pharmacology, College of Osteopathic Medicine, Des Moines University, Des Moines, Iowa, United States of America

  https://orcid.org/0000-0003-2346-9007

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• Jennifer Nguyen ,

  Contributed equally to this work with: Chia-Ming Lee, Jennifer Nguyen

  Roles Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

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• Brock Pope ,

  Roles Data curation, Investigation, Methodology

  ¶Deceased.

  Affiliation Department of Physiology and Pharmacology, College of Osteopathic Medicine, Des Moines University, Des Moines, Iowa, United States of America

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• Ali Sajid Imami,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

  ⨯
• V. William George Ryan,

  Roles Formal analysis, Visualization

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

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• Smita Sahay,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

  https://orcid.org/0009-0003-4377-8963

  ⨯
• Victoria Mathis,

  Roles Formal analysis, Visualization

  Affiliation Department of Physiology and Pharmacology, College of Osteopathic Medicine, Des Moines University, Des Moines, Iowa, United States of America

  ⨯
• Priyanka Pulvender,

  Roles Visualization

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

  https://orcid.org/0009-0006-3306-5195

  ⨯
• Hunter Michael Eby,

  Roles Visualization

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

  ⨯
• Taylen Arvay,

  Roles Visualization

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

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• Khaled Alganem,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

  Current address: The Medical Cities at the Ministry of Interior, Riyadh, Saudi Arabia

  Affiliation Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America

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• Lauren Wegman-Points,

  Roles Data curation, Investigation

  Affiliation Department of Physiology and Pharmacology, College of Osteopathic Medicine, Des Moines University, Des Moines, Iowa, United States of America

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• Robert McCullunsmith ,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: lilian.yuan@dmu.edu (LY); Robert.Mccullumsmith@UToledo.Edu (RM)

  Affiliations Department of Neurosciences and Psychiatry, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio, United States of America, ProMedica, Neurosciences Institute, Toledo, Ohio, United States of America

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• Li-Lian Yuan

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lilian.yuan@dmu.edu (LY); Robert.Mccullumsmith@UToledo.Edu (RM)

  Affiliation Department of Physiology and Pharmacology, College of Osteopathic Medicine, Des Moines University, Des Moines, Iowa, United States of America

  https://orcid.org/0000-0001-7787-576X

  ⨯