Effectiveness of Anti-SARS-CoV-2 monoclonal antibodies in real-life: RNAemia and clinical outcomes in high-risk COVID-19 patients

Matteo Domenico Marsiglia; Silvia Bianchi; Francesca Bai; Camilla Tincati; Emerenziana Ottaviano; Silvia Ancona; Giulia Marchetti; Elisa Borghi

doi:10.1371/journal.pone.0321356

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Open Access

Peer-reviewed

Research Article

Effectiveness of Anti-SARS-CoV-2 monoclonal antibodies in real-life: RNAemia and clinical outcomes in high-risk COVID-19 patients

Matteo Domenico Marsiglia,

Roles Data curation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Health Sciences, Università degli Studi di Milano, Milano, Italy

https://orcid.org/0009-0009-3421-9223

⨯
Silvia Bianchi ,

Roles Conceptualization, Writing – original draft, Writing – review & editing

* E-mail: silvia.bianchi@unimi.it

Affiliation Department of Health Sciences, Università degli Studi di Milano, Milano, Italy

https://orcid.org/0000-0002-1365-9408

⨯
Francesca Bai,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Clinic of Infectious Diseases, San Paolo Hospital, ASST Santi Paolo e Carlo, Department of Health Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Camilla Tincati,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliation Clinic of Infectious Diseases, San Paolo Hospital, ASST Santi Paolo e Carlo, Department of Health Sciences, Università degli Studi di Milano, Milano, Italy

https://orcid.org/0000-0002-3083-2962

⨯
Emerenziana Ottaviano,

Roles Methodology, Writing – review & editing

Affiliation Department of Health Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Silvia Ancona,

Roles Methodology, Writing – review & editing

Affiliation Department of Health Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Giulia Marchetti,

Roles Supervision, Writing – review & editing

Affiliation Clinic of Infectious Diseases, San Paolo Hospital, ASST Santi Paolo e Carlo, Department of Health Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Elisa Borghi

Roles Conceptualization, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Health Sciences, Università degli Studi di Milano, Milano, Italy
⨯

Effectiveness of Anti-SARS-CoV-2 monoclonal antibodies in real-life: RNAemia and clinical outcomes in high-risk COVID-19 patients

Matteo Domenico Marsiglia,
Silvia Bianchi,
Francesca Bai,
Camilla Tincati,
Emerenziana Ottaviano,
Silvia Ancona,
Giulia Marchetti,
Elisa Borghi

Published: April 25, 2025
https://doi.org/10.1371/journal.pone.0321356

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