A human antibody specific for SIRPα reprograms macrophages and promotes antibody mediated anti-cancer activity

• Keifer G. Kurtz,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliations Molecular Pharmacology Program, Sloan Kettering Institute, New York, United States of America, Pharmacology Program, Weill Cornell Medicine, New York, United States of America

  https://orcid.org/0000-0002-0988-1508

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• Irina Lebedeva,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• Stephanie A. Pierre,

  Roles Data curation, Investigation, Methodology

  Affiliations Molecular Pharmacology Program, Sloan Kettering Institute, New York, United States of America, Tri-Institutional MD-PhD Program, Weill Cornell Medicine, New York, United States of America

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• David Andrew,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• Yu-Rou Liao,

  Roles Data curation, Investigation, Methodology

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• Daisy Ambriz,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• Olivia Vergnolle,

  Roles Investigation, Methodology

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

  https://orcid.org/0000-0001-6885-6145

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• Leyi Shen,

  Roles Investigation, Project administration

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• Elizabeth Nyakatura,

  Roles Investigation, Methodology

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• Manuel Baca,

  Roles Conceptualization, Funding acquisition, Project administration

  Affiliation Tri-Institutional Therapeutics Discovery Institute, Weill Cornell Medicine, New York, United States of America

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• David A. Scheinberg

  Roles Conceptualization, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: scheinbd@mskcc.org

  Affiliations Molecular Pharmacology Program, Sloan Kettering Institute, New York, United States of America, Pharmacology Program, Weill Cornell Medicine, New York, United States of America, Department of Medicine, Memorial Hospital, New York, United States of America

  https://orcid.org/0000-0002-4160-923X

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