3D-MRI analysis of cartilage thickness changes after PRP injection in medial knee osteoarthritis: A preliminary report

Ichiro Sekiya; Hisako Katano; Mitsuru Mizuno; Kentaro Endo; Asuka Asami; Michiko Kajiwara; Naoki Otomo; Hideyuki Koga; Jun Masumoto; Nobutake Ozeki

doi:10.1371/journal.pone.0321067

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Open Access

Peer-reviewed

Research Article

3D-MRI analysis of cartilage thickness changes after PRP injection in medial knee osteoarthritis: A preliminary report

Ichiro Sekiya ,

Roles Conceptualization, Data curation, Formal analysis, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sekiya.arm@tmd.ac.jp

Affiliations Center for Stem Cell and Regenerative Medicine, Institute of Science, Tokyo, Japan, Blood Transfusion and Cell Therapy Center, Institute of Science, Tokyo, Japan

https://orcid.org/0000-0003-1671-5054

⨯
Hisako Katano,

Roles Conceptualization, Funding acquisition, Project administration

Affiliations Center for Stem Cell and Regenerative Medicine, Institute of Science, Tokyo, Japan, Blood Transfusion and Cell Therapy Center, Institute of Science, Tokyo, Japan
⨯
Mitsuru Mizuno,

Roles Data curation, Investigation

Affiliations Center for Stem Cell and Regenerative Medicine, Institute of Science, Tokyo, Japan, Blood Transfusion and Cell Therapy Center, Institute of Science, Tokyo, Japan
⨯
Kentaro Endo,

Roles Validation

Affiliation Center for Stem Cell and Regenerative Medicine, Institute of Science, Tokyo, Japan
⨯
Asuka Asami,

Roles Visualization

Affiliation Center for Stem Cell and Regenerative Medicine, Institute of Science, Tokyo, Japan
⨯
Michiko Kajiwara,

Roles Data curation, Investigation

Affiliation Blood Transfusion and Cell Therapy Center, Institute of Science, Tokyo, Japan
⨯
Naoki Otomo,

Roles Data curation, Investigation

Affiliation Blood Transfusion and Cell Therapy Center, Institute of Science, Tokyo, Japan
⨯
Hideyuki Koga,

Roles Validation

Affiliation Department of Joint Surgery and Sports Medicine, Graduate School of Medical and Dental Sciences, Institute of Science, Tokyo, Japan
⨯
Jun Masumoto,

Roles Software, Validation

Affiliation Fujifilm Corporation, Tokyo, Japan
⨯
Nobutake Ozeki

Roles Conceptualization, Investigation, Methodology, Project administration, Resources

Affiliation Center for Stem Cell and Regenerative Medicine, Institute of Science, Tokyo, Japan
⨯

3D-MRI analysis of cartilage thickness changes after PRP injection in medial knee osteoarthritis: A preliminary report

Ichiro Sekiya,
Hisako Katano,
Mitsuru Mizuno,
Kentaro Endo,
Asuka Asami,
Michiko Kajiwara,
Naoki Otomo,
Hideyuki Koga,
Jun Masumoto,
Nobutake Ozeki

Published: April 30, 2025
https://doi.org/10.1371/journal.pone.0321067

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Cartilage
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Knees
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Osteoarthritis
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Magnetic resonance imaging
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Skeletal joints
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