In silico studies provide new structural insights into trans-dimerization of β1 and β2 subunits of the Na+, K+-ATPase

Gema Ramírez-Salinas; Liora Shoshani; Jorge L. Rosas-Trigueros; Christian Sosa Huerta; Marlet Martínez-Archundia

doi:10.1371/journal.pone.0321064

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Peer-reviewed

Research Article

In silico studies provide new structural insights into trans-dimerization of β₁ and β₂ subunits of the Na⁺, K⁺-ATPase

Gema Ramírez-Salinas,

Roles Data curation, Formal analysis, Funding acquisition, Software, Supervision, Validation, Writing – original draft

Affiliation Laboratorio de Diseño y Desarrollo de Nuevos Fármacos e Innovación Biotecnológica (Laboratory for the Design and Development of New Drugs and Biotechnological Innovation), Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México
⨯
Liora Shoshani ,

Roles Conceptualization, Investigation, Project administration, Supervision, Visualization, Writing – original draft

* E-mail: shoshani@fisio.cinvestav.mx (LS); mtmartineza@ipn.mx (MMA)

Affiliation Department of Physiology, Biophysics, and Neurosciences, Center for Research and Advanced Studies (Cinvestav), Mexico City, Mexico

https://orcid.org/0000-0002-3442-4333

⨯
Jorge L. Rosas-Trigueros,

Roles Formal analysis, Methodology, Validation, Visualization, Writing – original draft

Affiliation Laboratorio Transdisciplinario de Investigación enSistemas Evolutivos, ESCOM, Instituto Politécnico Nacional, Mexico City, Mexico

https://orcid.org/0000-0003-2030-9817

⨯
Christian Sosa Huerta,

Roles Formal analysis, Investigation, Writing – original draft

Affiliation Department of Physiology, Biophysics, and Neurosciences, Center for Research and Advanced Studies (Cinvestav), Mexico City, Mexico
⨯
Marlet Martínez-Archundia

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft

* E-mail: shoshani@fisio.cinvestav.mx (LS); mtmartineza@ipn.mx (MMA)

Affiliation Laboratorio de Diseño y Desarrollo de Nuevos Fármacos e Innovación Biotecnológica (Laboratory for the Design and Development of New Drugs and Biotechnological Innovation), Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México, México

https://orcid.org/0000-0002-6140-8953

⨯

In silico studies provide new structural insights into trans-dimerization of β₁ and β₂ subunits of the Na⁺, K⁺-ATPase

Gema Ramírez-Salinas,
Liora Shoshani,
Jorge L. Rosas-Trigueros,
Christian Sosa Huerta,
Marlet Martínez-Archundia

Published: April 29, 2025
https://doi.org/10.1371/journal.pone.0321064

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