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Open Access
Peer-reviewed
Research Article
Mitochondria-targeted ROS scavenger JP4-039 improves cardiac function in a post-myocardial infarction animal model and induces angiogenesis in vitro
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Rayane Brinck Teixeira,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Jane H. Albro,
Roles Data curation, Formal analysis, Investigation, Writing – original draft
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Mohamed Sabra,
Roles Formal analysis, Writing – original draft
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Taslova Abedin,
Roles Methodology, Writing – original draft
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Aja N. Tucker,
Roles Formal analysis, Writing – original draft
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Raj Sidharth,
Roles Formal analysis
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Frank W. Sellke,
Roles Funding acquisition, Resources, Writing – review & editing
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Peter Wipf,
Roles Methodology, Resources, Writing – review & editing
Affiliations Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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M. Ruhul Abid
Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: ruhul_abid@brown.edu
Affiliation Department of Surgery, Division of Cardiothoracic Surgery, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
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Mitochondria-targeted ROS scavenger JP4-039 improves cardiac function in a post-myocardial infarction animal model and induces angiogenesis in vitro
- Rayane Brinck Teixeira,
- Jane H. Albro,
- Mohamed Sabra,
- Taslova Abedin,
- Aja N. Tucker,
- Raj Sidharth,
- Frank W. Sellke,
- Peter Wipf,
- M. Ruhul Abid
- Published: April 24, 2025
- https://doi.org/10.1371/journal.pone.0320703