Effect of opioid-free anesthesia combined with pectoral nerve block on the quality of recovery in patients after mastectomy: A randomized, controlled trial

Jiawei Chen; Lewei He; Yuying Shi; Jing Jiao; Shaoqiang Huang; Jianhua Zhou; Qingyan Luo

doi:10.1371/journal.pone.0320592

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Open Access

Peer-reviewed

Research Article

Effect of opioid-free anesthesia combined with pectoral nerve block on the quality of recovery in patients after mastectomy: A randomized, controlled trial

Jiawei Chen ,

Contributed equally to this work with: Jiawei Chen, Lewei He

Roles Conceptualization, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
⨯
Lewei He ,

Contributed equally to this work with: Jiawei Chen, Lewei He

Roles Conceptualization, Formal analysis, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
⨯
Yuying Shi,

Roles Data curation, Investigation, Methodology, Validation

Affiliation Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
⨯
Jing Jiao,

Roles Investigation, Resources, Supervision, Validation

Affiliation Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
⨯
Shaoqiang Huang,

Roles Investigation, Resources, Supervision, Validation, Visualization

Affiliation Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
⨯
Jianhua Zhou ,

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: wsqlqy@126.com

¶‡ JZ and QL also contributed equally to this work.

Affiliation Department of Anesthesiology, Huashan Hospital Fudan University, Shanghai, China
⨯
Qingyan Luo

Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: wsqlqy@126.com

¶‡ JZ and QL also contributed equally to this work.

Affiliation Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

https://orcid.org/0000-0001-5792-8668

⨯

Effect of opioid-free anesthesia combined with pectoral nerve block on the quality of recovery in patients after mastectomy: A randomized, controlled trial

Jiawei Chen,
Lewei He,
Yuying Shi,
Jing Jiao,
Shaoqiang Huang,
Jianhua Zhou,
Qingyan Luo

Published: April 3, 2025
https://doi.org/10.1371/journal.pone.0320592

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Surgical and invasive medical procedures
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Local and regional anesthesia
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Opioids
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