Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia

• Md. Arif Hossen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Umme Mim Sad Jahan,

  Roles Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Md. Arju Hossain,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Biochemistry and Biotechnology, Khwaja Yunus Ali University, Sirajganj, Bangladesh

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• Khalid Hossain Asif,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Ahona Rahman,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Sabbir Ahmed,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Md. Moin Uddin,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Biotechnology, Bangladesh Agricultural University, Mymensingh, Bangladesh

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• Md Faisal Amin,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

  https://orcid.org/0009-0009-9274-1335

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• Muhammad Abdul Barik,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Pharmacy, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Mohammod Johirul Islam,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Mohammad Kamruzzaman,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

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• Soharth Hasnat,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft

  Affiliations Molecular Biology and Bioinformatics Laboratory, Department of Gynecology, Obstetrics and Reproductive Health, Gazipur Agricultural University, Gazipur, Bangladesh, Institute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh

  https://orcid.org/0009-0008-3595-1179

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• Mohammad Nasir Uddin ,

  Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: nasir.bmb@mbstu.ac.bd (MNU); tofazzalislam@gau.edu.bd (TI); nazmul90@gau.edu.bd (MNH)

  Affiliation Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

  https://orcid.org/0000-0003-0223-9763

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• Tofazzal Islam ,

  Roles Conceptualization, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: nasir.bmb@mbstu.ac.bd (MNU); tofazzalislam@gau.edu.bd (TI); nazmul90@gau.edu.bd (MNH)

  Affiliation Institute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh

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• M. Nazmul Hoque

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – review & editing

  * E-mail: nasir.bmb@mbstu.ac.bd (MNU); tofazzalislam@gau.edu.bd (TI); nazmul90@gau.edu.bd (MNH)

  Affiliation Molecular Biology and Bioinformatics Laboratory, Department of Gynecology, Obstetrics and Reproductive Health, Gazipur Agricultural University, Gazipur, Bangladesh

  https://orcid.org/0000-0002-4861-0030

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