Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling

• Mei Li ,

  Contributed equally to this work with: Mei Li, Xiaoyan Hu

  Roles Project administration, Writing – original draft

  Affiliations Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China

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• Xiaoyan Hu ,

  Contributed equally to this work with: Mei Li, Xiaoyan Hu

  Roles Project administration, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

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• Xinxin Hu,

  Roles Conceptualization

  Affiliation Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

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• Fuhua Gao,

  Roles Visualization

  Affiliation Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

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• Ying Cui,

  Roles Formal analysis

  Affiliations Liaoning Provincial Core Lab of Medical Molecular Biology, Dalian Medical University, Dalian, China, Molecular Medicine Laboratory, Dalian Medical University, Dalian, China

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• Xiaoqing Wei,

  Roles Validation

  Affiliations Liaoning Provincial Core Lab of Medical Molecular Biology, Dalian Medical University, Dalian, China, Molecular Medicine Laboratory, Dalian Medical University, Dalian, China

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• Yuanhua Qin,

  Roles Formal analysis

  Affiliation Department of Parasite, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

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• Xiaohua An,

  Roles Resources

  Affiliation Clinical Laboratory, Dalian Central Hospital, Dalian, China

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• Ying Zhao ,

  Roles Validation

  * E-mail: gaoying200018@126.com (YG); zhaoying20001105@126.com (YZ)

  Affiliations Liaoning Provincial Core Lab of Medical Molecular Biology, Dalian Medical University, Dalian, China, Molecular Medicine Laboratory, Dalian Medical University, Dalian, China

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• Ying Gao

  Roles Writing – review & editing

  * E-mail: gaoying200018@126.com (YG); zhaoying20001105@126.com (YZ)

  Affiliations Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China, Liaoning Provincial Core Lab of Medical Molecular Biology, Dalian Medical University, Dalian, China, Molecular Medicine Laboratory, Dalian Medical University, Dalian, China

  https://orcid.org/0000-0002-5753-6944

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