Waning of anti-SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic in 2020: A 12-month-evaluation in three population-based European studies

Sophie Novelli; Christina Reinkemeyer; Dmitry Bulaev; Marc Paul O’Sullivan; Chantal J. Snoeck; Armin Rauschenberger; Carmelite Manto; Alexey Kolodkin; Soumyabrata Ghosh; Venkata Satagopam; Jerome le Chenadec; Karine Barthelemy; Stephane Priet; Xavier de Lamballerie; Andreas Wieser; Inge Kroidl; Michel Vaillant; Laurence Meyer; Michael Hoelscher; Noemi Castelletti; Rejko Krüger; Josiane Warszawski; for the ORCHESTRA Working Group

doi:10.1371/journal.pone.0320196

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Open Access

Peer-reviewed

Research Article

Waning of anti-SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic in 2020: A 12-month-evaluation in three population-based European studies

Sophie Novelli ,

Roles Writing – original draft, Writing – review & editing

* E-mail: sophie.novelli@inserm.fr

Affiliation Université Paris-Saclay, UVSQ, Inserm, CESP, APHP Hôpital Bicêtre, Le Kremlin-Bicêtre, France

https://orcid.org/0000-0003-0154-9786

⨯
Christina Reinkemeyer,

Roles Project administration, Writing – review & editing

Affiliations Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany
⨯
Dmitry Bulaev,

Roles Formal analysis, Writing – review & editing

Affiliation Luxembourg Institute of Health (LIH), Strassen, Luxembourg

https://orcid.org/0000-0002-0650-8871

⨯
Marc Paul O’Sullivan,

Roles Project administration, Writing – review & editing

Affiliation Luxembourg Institute of Health (LIH), Strassen, Luxembourg

https://orcid.org/0000-0002-6184-3306

⨯
Chantal J. Snoeck,

Roles Investigation, Writing – review & editing

Affiliation Luxembourg Institute of Health (LIH), Strassen, Luxembourg

https://orcid.org/0000-0002-0000-1850

⨯
Armin Rauschenberger,

Roles Investigation, Writing – review & editing

Affiliations Luxembourg Institute of Health (LIH), Strassen, Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg

https://orcid.org/0000-0001-6498-4801

⨯
Carmelite Manto,

Roles Project administration, Writing – review & editing

Affiliation Université Paris-Saclay, UVSQ, Inserm, CESP, Le Kremlin-Bicêtre, France
⨯
Alexey Kolodkin,

Roles Formal analysis

Affiliation Luxembourg Institute of Health (LIH), Strassen, Luxembourg
⨯
Soumyabrata Ghosh,

Roles Investigation

Affiliation Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
⨯
Venkata Satagopam,

Roles Investigation

Affiliation Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
⨯
Jerome le Chenadec,

Roles Formal analysis, Writing – review & editing

Affiliation Université Paris-Saclay, UVSQ, Inserm, CESP, Le Kremlin-Bicêtre, France
⨯
Karine Barthelemy,

Roles Investigation, Writing – review & editing

Affiliation Unité des Virus Emergents, UVE, Aix Marseille Université, Inserm, France

https://orcid.org/0000-0001-6343-2175

⨯
Stephane Priet,

Roles Investigation

Affiliation Unité des Virus Emergents, UVE, Aix Marseille Université, Inserm, France
⨯
Xavier de Lamballerie,

Roles Investigation, Writing – review & editing

Affiliation Unité des Virus Emergents, UVE, Aix Marseille Université, Inserm, France
⨯
Andreas Wieser,

Roles Conceptualization, Writing – review & editing

Affiliations Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany, German Center for Infection Research (DZIF), Munich, Germany, Max Von Pettenkofer Institute, Faculty of Medicine, LMU Munich, Munich, Germany
⨯
Inge Kroidl,

Roles Investigation

Affiliations Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany, German Center for Infection Research (DZIF), Munich, Germany
⨯
Michel Vaillant,

Roles Investigation, Writing – review & editing

Affiliation Luxembourg Institute of Health (LIH), Strassen, Luxembourg
⨯
Laurence Meyer,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Université Paris-Saclay, UVSQ, Inserm, CESP, APHP Hôpital Bicêtre, Le Kremlin-Bicêtre, France
⨯
Michael Hoelscher,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliations Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany, German Center for Infection Research (DZIF), Munich, Germany, Center for International Health (CIH), University Hospital, LMU Munich, Munich, Germany, Unit Global Health, Helmholtz Zentrum München, German Research Centre for Environmental Health (HMGU), Neuherberg, Germany
⨯
Noemi Castelletti,

Roles Formal analysis, Writing – review & editing

Affiliations Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany, German Center for Infection Research (DZIF), Munich, Germany, Institute of Radiation Medicine, Helmholtz Zentrum München, Neuherberg, Germany
⨯
Rejko Krüger,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliations Luxembourg Institute of Health (LIH), Strassen, Luxembourg, Centre Hospitalier de Luxembourg (CHL), Strassen, Luxembourg, Translational Neuroscience, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
⨯
Josiane Warszawski,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliation Université Paris-Saclay, UVSQ, Inserm, CESP, APHP Hôpital Bicêtre, Le Kremlin-Bicêtre, France

https://orcid.org/0000-0001-8590-7952

⨯
[ ... ],
for the ORCHESTRA Working Group

¶Membership of the ORCHESTRA working group is provided in the Supporting Information
⨯
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Waning of anti-SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic in 2020: A 12-month-evaluation in three population-based European studies

Sophie Novelli,
Christina Reinkemeyer,
Dmitry Bulaev,
Marc Paul O’Sullivan,
Chantal J. Snoeck,
Armin Rauschenberger,
Carmelite Manto,
Alexey Kolodkin,
Soumyabrata Ghosh,
Venkata Satagopam

Published: May 9, 2025
https://doi.org/10.1371/journal.pone.0320196

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