Long-term glycemic variability and the risk of cardiovascular diseases in type 2 diabetic patients: Effect of hypothetical interventions using parametric g-formula in a population-based historical cohort study

Khadije Maajani; Ensieh Nasli-Esfahani; Noushin Fahimfar; Ali Sheidaei; Mohammad Ali Mansournia; Kamran Yazdani

doi:10.1371/journal.pone.0319975

Loading metrics

Open Access

Peer-reviewed

Research Article

Long-term glycemic variability and the risk of cardiovascular diseases in type 2 diabetic patients: Effect of hypothetical interventions using parametric g-formula in a population-based historical cohort study

Khadije Maajani,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
⨯
Ensieh Nasli-Esfahani,

Roles Conceptualization, Data curation, Supervision, Writing – review & editing

Affiliation Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
⨯
Noushin Fahimfar,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
⨯
Ali Sheidaei,

Roles Formal analysis, Software, Writing – review & editing

Affiliation Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

https://orcid.org/0000-0002-0480-5768

⨯
Mohammad Ali Mansournia ,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: kyazdani48@yahoo.com (KY); mansournia_ma@yahoo.com (MAM)

Affiliation Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
⨯
Kamran Yazdani

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: kyazdani48@yahoo.com (KY); mansournia_ma@yahoo.com (MAM)

Affiliation Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

https://orcid.org/0000-0001-6666-1272

⨯

Long-term glycemic variability and the risk of cardiovascular diseases in type 2 diabetic patients: Effect of hypothetical interventions using parametric g-formula in a population-based historical cohort study

Khadije Maajani,
Ensieh Nasli-Esfahani,
Noushin Fahimfar,
Ali Sheidaei,
Mohammad Ali Mansournia,
Kamran Yazdani

Published: May 28, 2025
https://doi.org/10.1371/journal.pone.0319975

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cardiovascular diseases
Is the Subject Area "Cardiovascular diseases" applicable to this article?

Thanks for your feedback.
Cardiovascular disease risk
Is the Subject Area "Cardiovascular disease risk" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
HbA1c
Is the Subject Area "HbA1c" applicable to this article?

Thanks for your feedback.
Type 2 diabetes risk
Is the Subject Area "Type 2 diabetes risk" applicable to this article?

Thanks for your feedback.
Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Linear regression analysis
Is the Subject Area "Linear regression analysis" applicable to this article?

Thanks for your feedback.