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Open Access

Peer-reviewed

Research Article

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells

Qi Bao,

Roles Data curation, Formal analysis, Methodology, Resources, Writing – original draft

Affiliations Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China, Xuzhou Medical University, Xuzhou, Jiangsu, China, Department of Obstetrics and Gynecology, Liyang Peoples Hospital, Liyang, Jiangsu, China
⨯
Zihan Wang,

Roles Data curation, Methodology, Writing – original draft

Affiliation Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
⨯
Tingting Yang,

Roles Data curation, Methodology

Affiliation State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Soochow University, Suzhou, Jiangsu, China
⨯
Xiao Su,

Roles Formal analysis, Methodology, Software

Affiliations State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Soochow University, Suzhou, Jiangsu, China, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China
⨯
Ying Chen,

Roles Data curation, Formal analysis

Affiliation Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
⨯
Lifen Liu,

Roles Methodology, Software

Affiliation Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
⨯
Qicheng Deng,

Roles Data curation, Methodology

Affiliation Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
⨯
Qingyang Liu,

Roles Investigation

Affiliation Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

https://orcid.org/0009-0002-8535-7203

⨯
Changshun Shao,

Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Soochow University, Suzhou, Jiangsu, China

https://orcid.org/0000-0003-2618-9342

⨯
Weipei Zhu

Roles Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

* E-mail: zwp333xx@126.com

Affiliation Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

https://orcid.org/0000-0003-0737-9693

⨯

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells

Qi Bao,
Zihan Wang,
Tingting Yang,
Xiao Su,
Ying Chen,
Lifen Liu,
Qicheng Deng,
Qingyang Liu,
Changshun Shao,
Weipei Zhu

x

Published: March 31, 2025
https://doi.org/10.1371/journal.pone.0319846

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Ovarian cancer
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Cancer treatment
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Mitochondria
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Apoptosis
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Flow cytometry
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Cell cycle and cell division
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Oxidative stress
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DNA damage
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