Amoxicillin-induced bacterial gut dysbiosis decreases IL-1β and IL-6 expression but exacerbate lung inflammatory response against Mycobacterium bovis—Bacille Calmette-Guérin (BCG)

Tatimara M. Miyauchi-Tavares; Evandro Neves Silva; Joyce Alves dos Santos; Priscila V. Sousa; Marcos F. Teodoro Braga; Caroline M. Carminatti; Victoria B. Lanza; Bruna C. Fagundes; Rômulo Dias Novaes; Leonardo Augusto de Almeida; Patrícia Paiva Corsetti

doi:10.1371/journal.pone.0319382

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Peer-reviewed

Research Article

Amoxicillin-induced bacterial gut dysbiosis decreases IL-1β and IL-6 expression but exacerbate lung inflammatory response against Mycobacterium bovis—Bacille Calmette-Guérin (BCG)

Tatimara M. Miyauchi-Tavares,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Evandro Neves Silva,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Joyce Alves dos Santos,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Priscila V. Sousa,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Marcos F. Teodoro Braga,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Caroline M. Carminatti,

Roles Conceptualization, Formal analysis, Visualization

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Victoria B. Lanza,

Roles Conceptualization, Formal analysis, Visualization

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Bruna C. Fagundes,

Roles Conceptualization, Formal analysis, Visualization

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯
Rômulo Dias Novaes,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation

Affiliation Department of Structural Biology, Federal University of Alfenas (UNIFAL), Alfenas, Brazil
⨯
Leonardo Augusto de Almeida ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Resources, Supervision, Validation, Visualization, Writing – original draft

* E-mail: patricia.corsetti@unifal-mg.edu.br (PPC); leonardo.almeida@unifal-mg.edu.br (LAA)

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil

https://orcid.org/0000-0003-1886-5080

⨯
Patrícia Paiva Corsetti

Roles Conceptualization, Data curation, Formal analysis, Investigation, Resources, Supervision, Validation, Visualization, Writing – original draft

* E-mail: patricia.corsetti@unifal-mg.edu.br (PPC); leonardo.almeida@unifal-mg.edu.br (LAA)

Affiliation Laboratory of Molecular Biology of Microorganisms, Federal University of Alfenas (UNIFAL), Brazil
⨯

Amoxicillin-induced bacterial gut dysbiosis decreases IL-1β and IL-6 expression but exacerbate lung inflammatory response against Mycobacterium bovis—Bacille Calmette-Guérin (BCG)

Tatimara M. Miyauchi-Tavares,
Evandro Neves Silva,
Joyce Alves dos Santos,
Priscila V. Sousa,
Marcos F. Teodoro Braga,
Caroline M. Carminatti,
Victoria B. Lanza,
Bruna C. Fagundes,
Rômulo Dias Novaes,
Leonardo Augusto de Almeida

Published: February 26, 2025
https://doi.org/10.1371/journal.pone.0319382

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