X-ray crystallographic and hydrogen deuterium exchange studies confirm alternate kinetic models for homolog insulin monomers

• Esra Ayan ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: esraayan20@ku.edu.tr (EA); malp@medipol.edu.tr (MIA)

  Affiliations Department of Molecular Biology and Genetics, Faculty of Science, Koç University, Istanbul, Türkiye, Experimental Medicine Research and Application Center, University of Health Sciences, Istanbul, Türkiye, Research Institute for Health Sciences and Technologies (SABITA), Neuroscience Research Center, Istanbul Medipol University, Istanbul, Türkiye

  https://orcid.org/0000-0001-7906-4426

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• Miray Türk,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Department of Molecular Biology-Genetics and Biotechnology, Istanbul Technical University, Istanbul, Türkiye

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• Özge Tatlı,

  Roles Data curation, Software, Validation

  Affiliations Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden, Department of Molecular Biology and Genetics, Istanbul Medeniyet University, Istanbul, Türkiye

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• Sevginur Bostan,

  Roles Data curation, Formal analysis, Methodology, Software, Validation

  Affiliations Research Institute for Health Sciences and Technologies (SABITA), Neuroscience Research Center, Istanbul Medipol University, Istanbul, Türkiye, Department of Physiology, International School of Medicine, Istanbul Medipol University, Istanbul, Türkiye

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• Elek Telek,

  Roles Data curation, Methodology, Software, Validation

  Affiliation Department of Biophysics, Medical School, University of Pécs, Pécs, Hungary

  https://orcid.org/0000-0003-0396-4799

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• Baran Dingiloğlu,

  Roles Methodology, Software

  Affiliation Department of Molecular Biology-Genetics and Biotechnology, Istanbul Technical University, Istanbul, Türkiye

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• B. Züleyha Doğan,

  Roles Validation

  Affiliation Research Institute for Health Sciences and Technologies (SABITA), Neuroscience Research Center, Istanbul Medipol University, Istanbul, Türkiye

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• Muhammed Ikbal Alp ,

  Roles Resources

  * E-mail: esraayan20@ku.edu.tr (EA); malp@medipol.edu.tr (MIA)

  Affiliation Research Institute for Health Sciences and Technologies (SABITA), Neuroscience Research Center, Istanbul Medipol University, Istanbul, Türkiye

  https://orcid.org/0000-0003-2075-7724

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• Ahmet Katı,

  Roles Resources

  Affiliation Experimental Medicine Research and Application Center, University of Health Sciences, Istanbul, Türkiye

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• Gizem Dinler-Doğanay,

  Roles Conceptualization, Project administration, Resources, Supervision

  Affiliations Department of Molecular Biology-Genetics and Biotechnology, Istanbul Technical University, Istanbul, Türkiye, Department of Molecular Biology and Genetics, Faculty of Science and Letters, Istanbul Technical University, Istanbul, Türkiye

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• Hasan Demirci

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Molecular Biology and Genetics, Faculty of Science, Koç University, Istanbul, Türkiye, Stanford PULSE Institute, SLAC National Laboratory, Menlo Park, California, United States of America

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