Adaptation to acidic conditions that mimic the tumor microenvironment, downregulates miR-193b-3p, and induces EMT via TGFβ2 in A549 cells

• Sadayuki Higashi,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Munekazu Yamakuchi ,

  Roles Conceptualization, Supervision, Writing – review & editing

  * E-mail: k1581347@kadai.jp (TH); munekazu@m.kufm.kagoshima-u.ac.jp (MY)

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  https://orcid.org/0000-0003-2181-7194

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• Hirohito Hashinokuchi,

  Roles Investigation

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Kazunori Takenouchi,

  Roles Investigation

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Akito Tabaru,

  Roles Investigation

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  https://orcid.org/0000-0001-6018-9974

  ⨯
• Yoko Oyama,

  Roles Investigation

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Chieko Fujisaki,

  Roles Investigation

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Kiyonori Tanoue,

  Roles Data curation, Funding acquisition, Supervision

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Teruto Hashiguchi

  Roles Conceptualization, Supervision, Writing – review & editing

  * E-mail: k1581347@kadai.jp (TH); munekazu@m.kufm.kagoshima-u.ac.jp (MY)

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯