Home cage-based insights into motor learning and strategy adaptation in a Huntington disease mouse model

Daniel Ramandi; Marja D. Sepers; Zefang Wang; Brian Han; Cameron L. Woodard; Timothy H. Murphy; Lynn A. Raymond

doi:10.1371/journal.pone.0318663

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Open Access

Peer-reviewed

Research Article

Home cage-based insights into motor learning and strategy adaptation in a Huntington disease mouse model

Daniel Ramandi,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliations Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada, Graduate Program in Cell and Developmental Biology, University of British Columbia, Vancouver, British Columbia, Canada

https://orcid.org/0000-0003-2995-154X

⨯
Marja D. Sepers,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

https://orcid.org/0000-0002-6510-2804

⨯
Zefang Wang,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

https://orcid.org/0009-0006-9129-6821

⨯
Brian Han,

Roles Conceptualization, Data curation, Formal analysis, Software, Writing – review & editing

Affiliation Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

https://orcid.org/0009-0009-9348-6823

⨯
Cameron L. Woodard,

Roles Conceptualization, Methodology, Software, Writing – review & editing

Affiliation Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

https://orcid.org/0000-0002-7367-9670

⨯
Timothy H. Murphy,

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

https://orcid.org/0000-0002-0093-4490

⨯
Lynn A. Raymond

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: lynn.raymond@ubc.ca

Affiliation Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

https://orcid.org/0000-0002-8610-1042

⨯

Home cage-based insights into motor learning and strategy adaptation in a Huntington disease mouse model

Daniel Ramandi,
Marja D. Sepers,
Zefang Wang,
Brian Han,
Cameron L. Woodard,
Timothy H. Murphy,
Lynn A. Raymond

Published: February 13, 2025
https://doi.org/10.1371/journal.pone.0318663

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