Establishment of subcutaneous transplantation platform for delivering induced pluripotent stem cell-derived insulin-producing cells

Hong Thuan Tran; Watchareewan Rodprasert; Irma Padeta; Saranyou Oontawee; Steven dwi Purbantoro; Anatcha Thongsit; Parkpoom Siriarchavatana; Sayamon Srisuwatanasagul; Hiroshi Egusa; Thanaphum Osathanon; Chenphop Sawangmake

doi:10.1371/journal.pone.0318204

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Open Access

Peer-reviewed

Research Article

Establishment of subcutaneous transplantation platform for delivering induced pluripotent stem cell-derived insulin-producing cells

Hong Thuan Tran,

Roles Data curation, Formal analysis, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Second Century Fund (C2F) Chulalongkorn University for Doctoral Scholarship, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, The International Graduate Program of Veterinary Science and Technology (VST), Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand
⨯
Watchareewan Rodprasert,

Roles Conceptualization, Data curation, Methodology, Visualization, Writing – review & editing

Affiliations Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand
⨯
Irma Padeta,

Roles Methodology

Affiliations Second Century Fund (C2F) Chulalongkorn University for Doctoral Scholarship, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, The International Graduate Program of Veterinary Science and Technology (VST), Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand
⨯
Saranyou Oontawee,

Roles Methodology, Software

Affiliations Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand

https://orcid.org/0000-0001-6406-4124

⨯
Steven dwi Purbantoro,

Roles Methodology

Affiliations Second Century Fund (C2F) Chulalongkorn University for Doctoral Scholarship, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, The International Graduate Program of Veterinary Science and Technology (VST), Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand
⨯
Anatcha Thongsit,

Roles Methodology

Affiliations Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand
⨯
Parkpoom Siriarchavatana,

Roles Methodology

Affiliations Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Medicine, Western University, Kanchanaburi, Thailand

https://orcid.org/0000-0002-1104-8566

⨯
Sayamon Srisuwatanasagul,

Roles Methodology

Affiliation Faculty of Veterinary Science, Department of Anatomy, Chulalongkorn University, Bangkok, Thailand
⨯
Hiroshi Egusa,

Roles Supervision

Affiliation Division of Molecular and Regenerative Prosthodontics, Center for Advanced Stem Cell and Regenerative Research, Tohoku University Graduate School of Dentistry, Sendai, Japan
⨯
Thanaphum Osathanon,

Roles Supervision

Affiliations Faculty of Dentistry, Dental Stem Cell Biology Research Unit and Department of Anatomy, Chulalongkorn University, Bangkok, Thailand, Faculty of Dentistry, Center of Excellence in Regenerative Dentistry, Chulalongkorn University, Bangkok, Thailand

https://orcid.org/0000-0003-1649-6357

⨯
Chenphop Sawangmake

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: chenphop.s@chula.ac.th

Affiliations Faculty of Veterinary Science, Veterinary Clinical Stem Cell and Bioengineering Research Unit, Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC), Chulalongkorn University, Bangkok, Thailand, Faculty of Veterinary Science, Department of Pharmacology, Chulalongkorn University, Bangkok, Thailand

https://orcid.org/0000-0003-2619-9487

⨯

Establishment of subcutaneous transplantation platform for delivering induced pluripotent stem cell-derived insulin-producing cells

Hong Thuan Tran,
Watchareewan Rodprasert,
Irma Padeta,
Saranyou Oontawee,
Steven dwi Purbantoro,
Anatcha Thongsit,
Parkpoom Siriarchavatana,
Sayamon Srisuwatanasagul,
Hiroshi Egusa,
Thanaphum Osathanon

Published: January 30, 2025
https://doi.org/10.1371/journal.pone.0318204

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