Development of a unique crosslinked glycosaminoglycan for soft tissue repair: Treatment of interstitial cystitis/bladder pain syndrome

Richard W. Heidebrecht Jr.; Thomas H. Jozefiak; Harrison C. Shain; Eugene M. Skrabut; Debra Saunders; Nataliya Smith; Rheal A. Towner; Robert Hurst

doi:10.1371/journal.pone.0317790

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Open Access

Peer-reviewed

Research Article

Development of a unique crosslinked glycosaminoglycan for soft tissue repair: Treatment of interstitial cystitis/bladder pain syndrome

Richard W. Heidebrecht Jr. ,

Roles Conceptualization, Investigation, Project administration, Supervision, Writing – original draft

* E-mail: rich@glycologix.com

Affiliation Glycologix, Inc., 100 Cummings Center, Beverly, Massachusetts, United States of America

https://orcid.org/0009-0005-4470-0206

⨯
Thomas H. Jozefiak,

Roles Conceptualization, Writing – review & editing

Affiliation Glycologix, Inc., 100 Cummings Center, Beverly, Massachusetts, United States of America

https://orcid.org/0000-0001-8370-6102

⨯
Harrison C. Shain,

Roles Investigation, Writing – review & editing

Affiliation Glycologix, Inc., 100 Cummings Center, Beverly, Massachusetts, United States of America
⨯
Eugene M. Skrabut,

Roles Project administration, Writing – review & editing

Affiliation Glycologix, Inc., 100 Cummings Center, Beverly, Massachusetts, United States of America
⨯
Debra Saunders,

Roles Conceptualization, Data curation, Investigation, Visualization

Affiliation Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Nataliya Smith,

Roles Formal analysis, Investigation

Affiliation Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Rheal A. Towner,

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision

Affiliations Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada
⨯
Robert Hurst

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology

Affiliation Glycologix, Inc., 100 Cummings Center, Beverly, Massachusetts, United States of America
⨯

Development of a unique crosslinked glycosaminoglycan for soft tissue repair: Treatment of interstitial cystitis/bladder pain syndrome

Richard W. Heidebrecht Jr.,
Thomas H. Jozefiak,
Harrison C. Shain,
Eugene M. Skrabut,
Debra Saunders,
Nataliya Smith,
Rheal A. Towner,
Robert Hurst

Published: January 24, 2025
https://doi.org/10.1371/journal.pone.0317790

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