Anticryptosporidial action mechanisms of Launaea spinosa extracts in Cryptosporidium parvum experimentally infected mice in relation to its UHPLC-MS metabolite profile and biochemometric tools

• Mai M. Elghonemy ,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶☯ Equal contribution

  Affiliation Department of Natural Compounds Chemistry, National Research Centre, Giza, Egypt

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• Mohamed G. Sharaf El-Din ,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft

  ¶☯ Equal contribution

  Affiliation Pharmacognosy Department, Faculty of Pharmacy, Port Said University, Port Said, Egypt

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• Dina Aboelsoued ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

  ¶☯ Equal contribution

  Affiliation Parasitology and Animal Diseases Department, Veterinary Research Institute, National Research Centre, Giza, Egypt

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• Mohamed F. Abdelhameed,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Pharmacology Department, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt

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• Mohamed A. El-Saied,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt

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• Nagwa I. Toaleb,

  Roles Investigation, Methodology

  Affiliation Parasitology and Animal Diseases Department, Veterinary Research Institute, National Research Centre, Giza, Egypt

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• Mohamed A. Farag ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: elshamynrc@yahoo.com (AIE); mohamed.farag@pharma.cu.edu.eg (MAF)

  Affiliation Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt

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• Abdelsamed I. Elshamy ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  * E-mail: elshamynrc@yahoo.com (AIE); mohamed.farag@pharma.cu.edu.eg (MAF)

  Affiliation Department of Natural Compounds Chemistry, National Research Centre, Giza, Egypt

  https://orcid.org/0000-0003-3302-3623

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• Abdelbaset M. Elgamal

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Chemistry of Microbial and Natural Products, National Research Centre, Giza, Egypt

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