Mechanistic studies of PFKFB2 reveal a novel inhibitor of its kinase activity

• Craig Eyster ,

  Contributed equally to this work with: Craig Eyster, Satoshi Matsuzaki

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America,

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• Satoshi Matsuzaki ,

  Contributed equally to this work with: Craig Eyster, Satoshi Matsuzaki

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America,

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• Atul Pranay,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America,

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• Jennifer R. Giorgione,

  Roles Investigation

  Affiliation Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America,

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• Anna Faakye,

  Roles Investigation

  Affiliations Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America,, Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America,

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• Mostafa Ahmed,

  Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Atomwise Inc., San Francisco, California, United States of America

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• Kenneth M. Humphries

  Roles Conceptualization, Data curation, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Kenneth-Humphries@omrf.org

  Affiliations Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America,, Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America,

  https://orcid.org/0000-0002-6167-3175

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