MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban

Hongyu Li; Jimiao Qiu; Chang Liu; Guobing Yu; Danyu Wu; Yichun Chu; Kai Wang

doi:10.1371/journal.pone.0316887

Loading metrics

Open Access

Peer-reviewed

Research Article

MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban

Hongyu Li ,

Contributed equally to this work with: Hongyu Li, Jimiao Qiu, Chang Liu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation School of Nursing, NingBo College of Health Sciences, Ningbo, Zhejiang, China
⨯
Jimiao Qiu ,

Contributed equally to this work with: Hongyu Li, Jimiao Qiu, Chang Liu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Health Service, 906 Hospital of Joint Logistic Support Force of PLA, Ningbo, Zhejiang, China
⨯
Chang Liu ,

Contributed equally to this work with: Hongyu Li, Jimiao Qiu, Chang Liu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Respiratory Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
⨯
Guobing Yu,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Writing – original draft

Affiliation Department of Pathology, 906 Hospital of Joint Logistic Support Force of PLA, Ningbo, Zhejiang, China
⨯
Danyu Wu,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Pathology, 906 Hospital of Joint Logistic Support Force of PLA, Ningbo, Zhejiang, China
⨯
Yichun Chu,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Pathology, 906 Hospital of Joint Logistic Support Force of PLA, Ningbo, Zhejiang, China
⨯
Kai Wang

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: wkhhlr@qq.com

Affiliation Department of Pathology, 906 Hospital of Joint Logistic Support Force of PLA, Ningbo, Zhejiang, China

https://orcid.org/0009-0004-1682-7747

⨯

MicroRNA-221 protects myocardial contractility in myocardial ischemia/reperfusion injury through phospholamban

Hongyu Li,
Jimiao Qiu,
Chang Liu,
Guobing Yu,
Danyu Wu,
Yichun Chu,
Kai Wang

Published: January 30, 2025
https://doi.org/10.1371/journal.pone.0316887

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Myocardium
Is the Subject Area "Myocardium" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Cardiomyocytes
Is the Subject Area "Cardiomyocytes" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.