Mendelian randomization analysis to identify potential drug targets for osteoarthritis

Chengyang Lu; Yanan Xu; Shuai Chen; Li Guo; Pengcui Li; Xiaochun Wei; Xueqin Rong

doi:10.1371/journal.pone.0316824

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Open Access

Peer-reviewed

Research Article

Mendelian randomization analysis to identify potential drug targets for osteoarthritis

Chengyang Lu,

Roles Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Department of Orthopedics, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Yanan Xu,

Roles Conceptualization, Data curation, Investigation, Methodology, Software, Validation, Writing – review & editing

Affiliation Department of Laboratory, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Shuai Chen,

Roles Conceptualization, Data curation, Software, Writing – review & editing

Affiliation Department of Orthopedics, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Li Guo,

Roles Conceptualization, Investigation, Resources, Supervision, Validation, Writing – review & editing

Affiliation Department of Orthopedics, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Pengcui Li,

Roles Funding acquisition, Supervision, Validation, Writing – review & editing

Affiliation Department of Orthopedics, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Xiaochun Wei ,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: sdeygksys@163.com (XW); 13912048078@163.com (XR)

Affiliation Department of Orthopedics, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

https://orcid.org/0000-0002-6175-4346

⨯
Xueqin Rong

Roles Funding acquisition, Supervision, Validation, Writing – review & editing

* E-mail: sdeygksys@163.com (XW); 13912048078@163.com (XR)

Affiliation Department of Pain Medicine Center, The Central Hospital of Sanya, Sanya City, Hainan Province, China
⨯

Mendelian randomization analysis to identify potential drug targets for osteoarthritis

Chengyang Lu,
Yanan Xu,
Shuai Chen,
Li Guo,
Pengcui Li,
Xiaochun Wei,
Xueqin Rong

Published: February 11, 2025
https://doi.org/10.1371/journal.pone.0316824

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