Reduction of Cystatin B results in increased cathepsin B activity in disomic but not Trisomy 21 human cellular and mouse models

• Yixing Wu ,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  * E-mail: yixing.wu@ucl.ac.uk (YW); f.wiseman@ucl.ac.uk (FKW)

  Affiliations UK Dementia Research Institute at University College London, London, United Kingdom, UCL Queen Square Institute of Neurology, Queen Square, London, United Kingdom

  https://orcid.org/0000-0003-1150-9948

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• Karen Cleverley,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, London, United Kingdom

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• Frances K. Wiseman

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: yixing.wu@ucl.ac.uk (YW); f.wiseman@ucl.ac.uk (FKW)

  Affiliations UK Dementia Research Institute at University College London, London, United Kingdom, UCL Queen Square Institute of Neurology, Queen Square, London, United Kingdom

  https://orcid.org/0000-0001-9323-3548

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