A NOTCH3 pathogenic variant influences osteogenesis and can be targeted by antisense oligonucleotides in induced pluripotent stem cells

• Ernesto Canalis ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: canalis@uchc.edu

  Affiliations Departments of Orthopaedic Surgery, UConn Musculoskeletal Institute, UConn Health, Farmington, CT, United States of America, Departments of Medicine, UConn Musculoskeletal Institute, UConn Health, Farmington, CT, United States of America, UConn Musculoskeletal Institute, UConn Health, Farmington, CT, United States of America

  https://orcid.org/0000-0002-9154-952X

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• Jungeun Yu,

  Roles Investigation, Writing – review & editing

  Current address: Cellinfinity Bio, West Haven, CT, United States of America

  Affiliations Departments of Orthopaedic Surgery, UConn Musculoskeletal Institute, UConn Health, Farmington, CT, United States of America, UConn Musculoskeletal Institute, UConn Health, Farmington, CT, United States of America

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• Lauren Schilling,

  Roles Investigation, Visualization

  Affiliation UConn Musculoskeletal Institute, UConn Health, Farmington, CT, United States of America

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• Paymaan Jafar-nejad,

  Roles Resources, Visualization, Writing – review & editing

  Affiliation Ionis Pharmaceuticals, Inc., Carlsbad, CA, United States of America

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• Michele Carrer

  Roles Resources, Visualization, Writing – review & editing

  Affiliation Ionis Pharmaceuticals, Inc., Carlsbad, CA, United States of America

  https://orcid.org/0000-0002-6464-9584

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