Nanoencapsulation of amitriptyline enhances the potency of antidepressant-like effects and exhibits anxiolytic-like effects in Wistar rats

• Ramón Eduardo Valadez-Lemus,

  Roles Conceptualization, Data curation, Investigation, Writing – original draft

  Affiliation Facultad de Ciencias Químicas, Universidad de Colima, Colima, México

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• José L. Góngora-Alfaro,

  Roles Formal analysis, Methodology, Supervision

  Affiliation Centro de Investigaciones Regionales “Dr. Hideyo Noguchi”, Universidad Autónoma de Yucatán, Yucatán, México

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• Juana María Jiménez-Vargas,

  Roles Data curation, Methodology, Validation

  Affiliations Facultad de Ciencias Químicas, Universidad de Colima, Colima, México, Consejo Nacional de Humanidades Ciencia y Tecnología (CONAHCYT), México City, México

  https://orcid.org/0000-0001-9508-9332

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• Javier Alamilla ,

  Roles Conceptualization, Formal analysis, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: alamilla78@gmail.com, jfalamillago@conahcyt.mx (JA); nmendoza0@ucol.mx (NM-M)

  Affiliations Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Colima, México, Investigador por México-CONAHCYT-Universidad de Colima, Colima, México

  https://orcid.org/0000-0002-9666-5490

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• Néstor Mendoza-Muñoz

  Roles Conceptualization, Funding acquisition, Validation, Writing – review & editing

  * E-mail: alamilla78@gmail.com, jfalamillago@conahcyt.mx (JA); nmendoza0@ucol.mx (NM-M)

  Affiliation Facultad de Ciencias Químicas, Universidad de Colima, Colima, México

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