Evaluation of the effect of cell freshness on pyrogen detection using a serum-free monocyte-activation test

• Katsuhiko Hayashi ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: hayashi_katsuhiko@nihs.go.jp

  Affiliation Division of Microbiology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan

  https://orcid.org/0000-0001-7359-5939

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• Mizuki Sano,

  Roles Investigation

  Affiliation Department of Infection Control Science, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan

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• Toshie Kanayasu-Toyoda,

  Roles Investigation, Methodology

  Affiliation Department of Pharmaceutical and Medical Business Sciences, Nihon Pharmaceutical University, Kitaadachi-gun, Saitama, Japan

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• Yuji Morita,

  Roles Methodology

  Affiliation Department of Infection Control Science, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan

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• Teruhide Yamaguchi,

  Roles Methodology

  Affiliations Department of Pharmaceutical and Medical Business Sciences, Nihon Pharmaceutical University, Kitaadachi-gun, Saitama, Japan, Institute of Advanced Medical and Engineering Technology for Aging, Kanazawa Institute of Technology. Nonoichi, Ishikawa, Japan

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• Kenji Ohya,

  Roles Methodology

  Affiliation Division of Microbiology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan

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• Yutaka Kikuchi,

  Roles Methodology

  Affiliation Department of Nutrition, Faculty of Healthcare Sciences, Chiba Prefectural University of Health Sciences, Chiba, Japan

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• Ken-ichi Izutsu,

  Roles Funding acquisition

  Affiliation Department of Pharmaceutical Sciences, School of Pharmacy International University of Health and Welfare, Ohtawara, Tochigi, Japan

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• Yukiko Hara-Kudo

  Roles Funding acquisition, Supervision

  Affiliations Division of Microbiology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan

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