Plasma and serum concentrations of VEGF-A121, but not of VEGF-A165, increase post-bevacizumab administration

• Masashi Okawa ,

  Contributed equally to this work with: Masashi Okawa, Munekazu Yamakuchi

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Munekazu Yamakuchi ,

  Contributed equally to this work with: Masashi Okawa, Munekazu Yamakuchi

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  * E-mail: k1581347@kadai.jp (TH); munekazu@m.kufm.kagoshima-u.ac.jp (MY)

  Affiliations Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  https://orcid.org/0000-0003-2181-7194

  ⨯
• Aryal Bibek,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Kazunori Takenouchi,

  Roles Data curation, Funding acquisition, Investigation, Methodology

  Affiliations Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  https://orcid.org/0000-0003-1946-457X

  ⨯
• Drew N. Maywar,

  Roles Formal analysis, Writing – review & editing

  Affiliation Electrical and Computer Engineering Technology, Rochester Institute of Technology, Rochester, New York, United States of America

  https://orcid.org/0000-0002-2674-0520

  ⨯
• Shingo Yamada,

  Roles Methodology, Resources

  Affiliation Shino-Test Corporation, Sagamihara, Japan

  ⨯
• Keiichi Inoue,

  Roles Conceptualization, Methodology, Resources

  Affiliation Shino-Test Corporation, Sagamihara, Japan

  ⨯
• Kazuhiko Higurashi,

  Roles Methodology, Resources

  Affiliation Shino-Test Corporation, Sagamihara, Japan

  ⨯
• Junichi Nakazawa,

  Roles Resources

  Affiliation Department of Medical Oncology, Kagoshima City Hospital, Kagoshima, Japan

  ⨯
• Masahiro Kawahira,

  Roles Resources

  Affiliation Department of Medical Oncology, Kagoshima City Hospital, Kagoshima, Japan

  ⨯
• Tomoko Kodama,

  Roles Resources

  Affiliation Department of Medical Oncology, Kagoshima City Hospital, Kagoshima, Japan

  ⨯
• Kiyonori Tanoue,

  Roles Investigation

  Affiliation Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  ⨯
• Yoko Oyama,

  Roles Investigation

  Affiliations Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  ⨯
• Sadayuki Higashi,

  Roles Investigation

  Affiliations Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  ⨯
• Chieko Fujisaki,

  Roles Investigation

  Affiliations Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  ⨯
• Hirohito Hashinokuchi,

  Roles Investigation

  Affiliation Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  ⨯
• Akito Tabaru,

  Roles Investigation

  Affiliation Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Hideaki Kanda,

  Roles Investigation

  Affiliation Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Shuji Tachioka,

  Roles Investigation

  Affiliation Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Yutaka Imoto,

  Roles Funding acquisition, Resources

  Affiliation Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  ⨯
• Teruto Hashiguchi ,

  Roles Conceptualization, Data curation, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: k1581347@kadai.jp (TH); munekazu@m.kufm.kagoshima-u.ac.jp (MY)

  Affiliations Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, Kagoshima University Hospital Clinical Laboratory, Kagoshima, Japan

  ⨯
•  [ ... ],
• Yoshiharu Soga

  Roles Funding acquisition, Resources

  Affiliation Department of Cardiovascular and Gastroenterological Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

  https://orcid.org/0000-0001-6718-6960

  ⨯
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