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Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model
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Manuel E. Lopez ,
Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing
* E-mail: manny.lopez@bmrn.com
Affiliation BioMarin Pharmaceutical Inc., Novato, CA, United States of America
⨯ - Daniel Wendt,
- Roger Lawrence,
- Kerui Gong,
- Hoonsan Ong,
- Bryan Yip,
- Joseph Chen,
- Linley Mangini,
- Britta Handyside,
- Alexander Giaramita,
- Aashish Lamichhane,
- Melanie Lo,
- Vishal Agrawal,
- Jeremy Van Vleet,
- Amanda Abolhesn,
- Jessica B. Felix,
- Isaac Villalpando,
- Vikas Bhat,
- Rolando De Angelis,
- Yuanbin Ru,
- Ayesha Khan,
- Sylvia Fong,
- Terri Christianson,
- Sherry Bullens,
- Brett E. Crawford,
- Stuart Bunting,
- [ ... ],
- Mika Aoyagi-Scharber
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https://orcid.org/0000-0002-0982-2137
Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model
- Manuel E. Lopez,
- Daniel Wendt,
- Roger Lawrence,
- Kerui Gong,
- Hoonsan Ong,
- Bryan Yip,
- Joseph Chen,
- Linley Mangini,
- Britta Handyside,
- Alexander Giaramita
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- Published: January 3, 2025
- https://doi.org/10.1371/journal.pone.0315005