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Open Access
Peer-reviewed
Research Article
FORCETRACKER: A versatile tool for standardized assessment of tissue contractile properties in 3D Heart-on-Chip platforms
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José M. Rivera-Arbeláez ,
Contributed equally to this work with: José M. Rivera-Arbeláez, Milica Dostanić
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft
Affiliations MESA+Institute for Nanotechnology, BIOS Lab on a Chip Group, Technical Medical Centre, Max Planck Center for Com-plex Fluid Dynamics, University of Twente, Enschede, The Netherlands, Department of Bioengineering Technologies, Applied Stem Cell Technologies Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands
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Milica Dostanić ,
Contributed equally to this work with: José M. Rivera-Arbeláez, Milica Dostanić
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft
Affiliation Microelectronics, Delft University of Technology, Delft, The Netherlands
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Laura M. Windt,
Roles Investigation, Writing – review & editing
Affiliation Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands
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Jeroen M. Stein,
Roles Investigation, Writing – review & editing
Affiliation Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands
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Carla Cofiño-Fabres,
Roles Investigation, Writing – review & editing
Affiliation Department of Bioengineering Technologies, Applied Stem Cell Technologies Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands
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Tom Boonen,
Roles Investigation, Writing – review & editing
Affiliation River BioMedics, Enschede, The Netherlands
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Maury Wiendels,
Roles Investigation, Writing – review & editing
Affiliation Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands
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Albert van den Berg,
Roles Funding acquisition, Writing – review & editing
Affiliation MESA+Institute for Nanotechnology, BIOS Lab on a Chip Group, Technical Medical Centre, Max Planck Center for Com-plex Fluid Dynamics, University of Twente, Enschede, The Netherlands
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Loes I. Segerink,
Roles Funding acquisition, Writing – review & editing
Affiliation MESA+Institute for Nanotechnology, BIOS Lab on a Chip Group, Technical Medical Centre, Max Planck Center for Com-plex Fluid Dynamics, University of Twente, Enschede, The Netherlands
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Christine L. Mummery,
Roles Funding acquisition, Writing – review & editing
Affiliations Department of Bioengineering Technologies, Applied Stem Cell Technologies Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands, Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands
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Pasqualina M. Sarro,
Roles Funding acquisition
Affiliation Microelectronics, Delft University of Technology, Delft, The Netherlands
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Berend J. van Meer,
Roles Supervision, Writing – review & editing
Affiliation Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands
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Marcelo C. Ribeiro,
Roles Supervision, Writing – review & editing
Affiliation River BioMedics, Enschede, The Netherlands
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Massimo Mastrangeli,
Roles Supervision, Writing – review & editing
Affiliation Microelectronics, Delft University of Technology, Delft, The Netherlands
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Robert Passier
Roles Funding acquisition, Supervision, Writing – review & editing
* E-mail: robert.passier@utwente.nl
Affiliations Department of Bioengineering Technologies, Applied Stem Cell Technologies Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands, Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden, The Netherlands
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FORCETRACKER: A versatile tool for standardized assessment of tissue contractile properties in 3D Heart-on-Chip platforms
- José M. Rivera-Arbeláez,
- Milica Dostanić,
- Laura M. Windt,
- Jeroen M. Stein,
- Carla Cofiño-Fabres,
- Tom Boonen,
- Maury Wiendels,
- Albert van den Berg,
- Loes I. Segerink,
- Christine L. Mummery
- Published: February 13, 2025
- https://doi.org/10.1371/journal.pone.0314985