Moderate static magnetic fields prevent estrogen deficiency-induced bone loss: Evidence from ovariectomized mouse model and small sample size randomized controlled clinical trial

Shenghang Wang; Jiancheng Yang; Yunpeng Wei; Chao Cai; Shuai Chen; Youde Wu; Xiao Li; Lilei Sun; Xianglin Li; Ming Gong; Jianhua Zhou; Yawei Hu; Wang Zhang; Zengfeng Guo; Jiacheng Liao; Chunling Luo; Xiaosu Bai; Xinle luo; Liming Duan; Ting Huyan; Zhouqi Yang; Min Wei; Yanwen Fang; Hao Zhang; Peng Shang

doi:10.1371/journal.pone.0314199

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Open Access

Peer-reviewed

Research Article

Moderate static magnetic fields prevent estrogen deficiency-induced bone loss: Evidence from ovariectomized mouse model and small sample size randomized controlled clinical trial

Shenghang Wang ,

Contributed equally to this work with: Shenghang Wang, Jiancheng Yang

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

Affiliations Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China, Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China
⨯
Jiancheng Yang ,

Contributed equally to this work with: Shenghang Wang, Jiancheng Yang

Roles Data curation, Investigation, Methodology, Software, Supervision, Writing – original draft

Affiliation Department of Osteoporosis, Honghui Hospital, Xi'an Jiaotong University, Xi'an, China
⨯
Yunpeng Wei,

Roles Data curation, Investigation, Methodology

Affiliation Shenzhen University of Advanced Technology, Shenzhen, China
⨯
Chao Cai,

Roles Data curation, Methodology

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Shuai Chen,

Roles Data curation, Investigation

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Youde Wu,

Roles Data curation, Methodology

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Xiao Li,

Roles Data curation, Investigation

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Lilei Sun,

Roles Data curation, Investigation

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Xianglin Li,

Roles Data curation, Investigation

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Ming Gong,

Roles Data curation, Investigation

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
Jianhua Zhou,

Roles Data curation, Investigation

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
Yawei Hu,

Roles Data curation, Investigation

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
Wang Zhang,

Roles Data curation, Methodology

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
Zengfeng Guo,

Roles Data curation, Investigation

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
Jiacheng Liao,

Roles Data curation, Investigation, Methodology, Supervision

Affiliation Minle Community Health Service Center, People's Hospital of Longhua, Shenzhen, China
⨯
Chunling Luo,

Roles Data curation, Investigation, Methodology, Supervision

Affiliation Minle Community Health Service Center, People's Hospital of Longhua, Shenzhen, China
⨯
Xiaosu Bai,

Roles Conceptualization, Methodology, Supervision

Affiliation Department of Endocrinology, People's Hospital of Longhua, Shenzhen, China
⨯
Xinle luo,

Roles Methodology

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
Liming Duan,

Roles Software, Supervision

Affiliation An Shi Rui Information Technology Co., Ltd, Shenzhen, China
⨯
Ting Huyan,

Roles Formal analysis, Investigation

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Zhouqi Yang,

Roles Methodology, Project administration

Affiliations Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China
⨯
Min Wei,

Roles Conceptualization, Project administration, Supervision

Affiliation Heye Health Technology Co., Ltd, Huzhou, China
⨯
Yanwen Fang,

Roles Data curation, Investigation, Supervision

Affiliation Heye Health Technology Co., Ltd, Huzhou, China
⨯
Hao Zhang ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Resources, Writing – review & editing

* E-mail: shangpeng@nwpu.edu.cn (PS); zhanghaodoctor1@hotmail.com (HZ)

Affiliation Department of Spine Surgery, People's Hospital of Longhua, Shenzhen, China
⨯
[ ... ],
Peng Shang

Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

* E-mail: shangpeng@nwpu.edu.cn (PS); zhanghaodoctor1@hotmail.com (HZ)

Affiliation Research & Development Institute of Northwestern Polytechnical University in Shenzhen, Shenzhen, China

https://orcid.org/0000-0001-5418-6240

⨯
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Moderate static magnetic fields prevent estrogen deficiency-induced bone loss: Evidence from ovariectomized mouse model and small sample size randomized controlled clinical trial

Shenghang Wang,
Jiancheng Yang,
Yunpeng Wei,
Chao Cai,
Shuai Chen,
Youde Wu,
Xiao Li,
Lilei Sun,
Xianglin Li,
Ming Gong

Published: April 29, 2025
https://doi.org/10.1371/journal.pone.0314199

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