Examining heterogeneity in dementia using data-driven unsupervised clustering of cognitive profiles

Sayantan Kumar; Inez Y. Oh; Suzanne E. Schindler; Nupur Ghoshal; Zachary Abrams; Philip R. O. Payne

doi:10.1371/journal.pone.0313425

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Open Access

Peer-reviewed

Research Article

Examining heterogeneity in dementia using data-driven unsupervised clustering of cognitive profiles

Sayantan Kumar ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sayantan.kumar@wustl.edu

Affiliations Department of Computer Science and Engineering, McKelvey School of Engineering, Washington University in St Louis, St. Louis, Missouri, United States of America, Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University School of Medicine, St. Louis, Missouri, United States of America

https://orcid.org/0000-0001-7213-0734

⨯
Inez Y. Oh,

Roles Writing – review & editing

Affiliation Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Suzanne E. Schindler,

Roles Writing – review & editing

Affiliation Division of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America

https://orcid.org/0000-0002-1680-1465

⨯
Nupur Ghoshal,

Roles Writing – review & editing

Affiliations Division of Neurology, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, United States of America

https://orcid.org/0000-0002-6680-6731

⨯
Zachary Abrams,

Roles Conceptualization, Methodology, Software, Supervision, Validation, Writing – review & editing

Affiliation Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Philip R. O. Payne

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

Affiliations Department of Computer Science and Engineering, McKelvey School of Engineering, Washington University in St Louis, St. Louis, Missouri, United States of America, Institute for Informatics, Data Science and Biostatistics (I2DB), Washington University School of Medicine, St. Louis, Missouri, United States of America

https://orcid.org/0000-0002-9532-2998

⨯

Examining heterogeneity in dementia using data-driven unsupervised clustering of cognitive profiles

Sayantan Kumar,
Inez Y. Oh,
Suzanne E. Schindler,
Nupur Ghoshal,
Zachary Abrams,
Philip R. O. Payne

Published: November 14, 2024
https://doi.org/10.1371/journal.pone.0313425

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Dementia
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Cognitive impairment
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Memory
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Electronic medical records
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Clustering algorithms
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