Prolactin protects hippocampal neurons against H2O2-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway

Fernando Macías; Miriam Ulloa; Carmen Clapp; Gonzalo Martínez de la Escalera; Edith Arnold

doi:10.1371/journal.pone.0313328

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Peer-reviewed

Research Article

Prolactin protects hippocampal neurons against H₂O₂-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway

Fernando Macías,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, Querétaro, Querétaro, México
⨯
Miriam Ulloa,

Roles Formal analysis, Investigation

Affiliation Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, Querétaro, Querétaro, México
⨯
Carmen Clapp,

Roles Resources, Supervision, Writing – review & editing

Affiliation Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, Querétaro, Querétaro, México
⨯
Gonzalo Martínez de la Escalera ,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: earnoldh@gmail.com (EA); gmel@unam.mx (GME)

Affiliation Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, Querétaro, Querétaro, México

https://orcid.org/0000-0002-4309-3476

⨯
Edith Arnold

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: earnoldh@gmail.com (EA); gmel@unam.mx (GME)

Affiliations Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, Querétaro, Querétaro, México, CONAHCYT–Instituto de Neurobiología, Universidad Nacional Autónoma de México (UNAM), Campus UNAM-Juriquilla, Querétaro, Querétaro, México
⨯

Prolactin protects hippocampal neurons against H₂O₂-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway

Fernando Macías,
Miriam Ulloa,
Carmen Clapp,
Gonzalo Martínez de la Escalera,
Edith Arnold

Published: November 5, 2024
https://doi.org/10.1371/journal.pone.0313328

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Hippocampus
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Neurons
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Prolactin
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