Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo

• Buthaina Al Shueili,

  Roles Formal analysis, Investigation, Validation, Writing – original draft

  Current address: Department of Biology, College of Science, Sultan Qaboos University, Muscat, Oman

  Affiliations Robson DNA Sciences Centre, Calgary, Canada, Arnie Charbonneau Cancer Institute, Calgary, Canada, Departments of Biochemistry & Molecular Biology, University of Calgary, Calgary, Canada

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• Arthur Dantas,

  Roles Formal analysis, Investigation

  Current address: Faculty of Health Sciences, School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada

  Affiliations Robson DNA Sciences Centre, Calgary, Canada, Arnie Charbonneau Cancer Institute, Calgary, Canada

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• Etienne Mahe,

  Roles Formal analysis, Investigation

  Affiliations Arnie Charbonneau Cancer Institute, Calgary, Canada, Departments of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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• Tak Ho Chu,

  Roles Investigation, Supervision

  Affiliations Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, Departments of Clinical Neurosciences, University of Calgary, Calgary, Canada

  https://orcid.org/0000-0002-3123-207X

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• Yang Yang,

  Roles Investigation, Project administration

  Affiliations Robson DNA Sciences Centre, Calgary, Canada, Arnie Charbonneau Cancer Institute, Calgary, Canada, Departments of Alberta Children’s Hospital Research Institute, University of Calgary, Calgary, Canada

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• Elodie Labit,

  Roles Investigation

  Affiliation Departments of Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Canada

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• Eren Kutluberk,

  Roles Investigation

  Affiliation Departments of Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Canada

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• Nicolas Lasaleta,

  Roles Investigation

  Affiliations Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, Departments of Clinical Neurosciences, University of Calgary, Calgary, Canada

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• Anand Masson,

  Roles Investigation

  Affiliations Departments of McCaig Institute for Bone & Joint Health, University of Calgary, Calgary, Canada, Departments of Cell Biology and Anatomy, University of Calgary, Calgary, Canada

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• Hiba Omairi,

  Roles Formal analysis, Investigation

  Affiliations Arnie Charbonneau Cancer Institute, Calgary, Canada, Departments of Biochemistry & Molecular Biology, University of Calgary, Calgary, Canada

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• Kenichi Ito,

  Roles Formal analysis

  Affiliation Departments of Biochemistry & Molecular Biology, University of Calgary, Calgary, Canada

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• Roman J. Krawetz,

  Roles Supervision

  Affiliations Departments of McCaig Institute for Bone & Joint Health, University of Calgary, Calgary, Canada, Departments of Cell Biology and Anatomy, University of Calgary, Calgary, Canada, Departments of Surgery, University of Calgary, Calgary, Canada

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• Rajiv Midha,

  Roles Project administration, Resources

  Affiliations Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, Departments of Clinical Neurosciences, University of Calgary, Calgary, Canada

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• Gregory Cairncross,

  Roles Resources, Supervision

  Affiliations Arnie Charbonneau Cancer Institute, Calgary, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, Departments of Oncology, University of Calgary, Calgary, Canada

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• Karl Riabowol

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: karl@ucalgary.ca

  Affiliations Robson DNA Sciences Centre, Calgary, Canada, Arnie Charbonneau Cancer Institute, Calgary, Canada, Departments of Biochemistry & Molecular Biology, University of Calgary, Calgary, Canada, Departments of Alberta Children’s Hospital Research Institute, University of Calgary, Calgary, Canada, Departments of Oncology, University of Calgary, Calgary, Canada

  https://orcid.org/0000-0002-5318-2536

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