Versatile properties of Opuntia ficus-indica (L.) Mill. flowers: In vitro exploration of antioxidant, antimicrobial, and anticancer activities, network pharmacology analysis, and In-silico molecular docking simulation

• Mai Ali Mwaheb ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: melwatidy@ksu.edu.sa (MSE-W); mam08@fayoum.edu.eg (MAM); Dr.nashwa_ezzelarab@yahoo.com (NMR)

  Affiliation Botany Department, Faculty of Science, Fayoum University, Fayoum, Egypt

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• Nashwa Mohamed Reda ,

  Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: melwatidy@ksu.edu.sa (MSE-W); mam08@fayoum.edu.eg (MAM); Dr.nashwa_ezzelarab@yahoo.com (NMR)

  Affiliation Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt

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• Mohammad S. El-Wetidy ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Validation, Writing – original draft, Writing – review & editing

  * E-mail: melwatidy@ksu.edu.sa (MSE-W); mam08@fayoum.edu.eg (MAM); Dr.nashwa_ezzelarab@yahoo.com (NMR)

  Affiliation Core Facility Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia

  https://orcid.org/0000-0003-2725-4708

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• Asmaa H. Sheded,

  Roles Data curation, Methodology, Validation, Writing – original draft

  Affiliation Organic Chemistry Department, Faculty of Science, Ain-Shams University, Cairo, Egypt

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• Fatimah Al-Otibi,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia

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• Gadah A. Al-Hamoud,

  Roles Funding acquisition, Methodology

  Affiliation Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

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• Mohamed A. Said,

  Roles Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft

  Affiliation Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt

  https://orcid.org/0000-0002-7937-0084

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• Esraa A. Aidy

  Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Cancer Biology Department, Medical Biochemistry and Molecular Biology Unit, National Cancer Institute, Cairo University, Cairo, Egypt

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