Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization

Zhengze Zhang; Yanan Lian; Yuewen He; Hao Liu; Kai Meng; Yong Wang; Wuhua Ma

doi:10.1371/journal.pone.0313032

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Open Access

Peer-reviewed

Research Article

Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization

Zhengze Zhang ,

Contributed equally to this work with: Zhengze Zhang, Yanan Lian

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliations The First Clinical Medical School of Guangzhou University of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China, Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China
⨯
Yanan Lian ,

Contributed equally to this work with: Zhengze Zhang, Yanan Lian

Roles Conceptualization, Data curation, Methodology, Writing – original draft

Affiliation Shandong Mental Health Center, Jinan, Shandong, PR China
⨯
Yuewen He,

Roles Conceptualization, Methodology, Writing – original draft

Affiliations The First Clinical Medical School of Guangzhou University of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China, Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China
⨯
Hao Liu,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliations The First Clinical Medical School of Guangzhou University of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China, Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China
⨯
Kai Meng ,

Roles Conceptualization, Supervision, Writing – review & editing

* E-mail: sdmengkai2016@163.com (KM); tuesdaymorninggz@126.com (WM)

Affiliation Department of Orthopaedics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, PR China
⨯
Yong Wang,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China
⨯
Wuhua Ma

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: sdmengkai2016@163.com (KM); tuesdaymorninggz@126.com (WM)

Affiliation Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China

https://orcid.org/0000-0003-1277-1681

⨯

Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization

Zhengze Zhang,
Yanan Lian,
Yuewen He,
Hao Liu,
Kai Meng,
Yong Wang,
Wuhua Ma

Published: January 9, 2025
https://doi.org/10.1371/journal.pone.0313032

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Stroke
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