(−)-Epicatechin regulates endoplasmic reticulum stress and promotes ferroptosis in lung cancer cells via the PERK/eIF2α/ATF4 signaling pathway

• Zengbo Lv ,

  Contributed equally to this work with: Zengbo Lv, Peiwan Liu, Yingyu Yang

  Roles Conceptualization, Funding acquisition, Validation, Writing – original draft

  Affiliation Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Peiwan Liu ,

  Contributed equally to this work with: Zengbo Lv, Peiwan Liu, Yingyu Yang

  Roles Conceptualization, Validation, Writing – original draft

  Affiliation Department of Hepatobiliary Surgery, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Yingyu Yang ,

  Contributed equally to this work with: Zengbo Lv, Peiwan Liu, Yingyu Yang

  Roles Conceptualization, Methodology, Visualization, Writing – original draft

  Affiliation Department of Pathology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Jianhua Ji,

  Roles Methodology

  Affiliation Department of Radiotherapy, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

  ⨯
• Anao Wu,

  Roles Data curation, Methodology

  Affiliation Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Wensheng Huang,

  Roles Data curation

  Affiliation Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Liqiong Zhang,

  Roles Formal analysis

  Affiliation Geriatrics Department, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Zhijun Zhang,

  Roles Formal analysis

  Affiliation Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Yunkui Yang,

  Roles Software

  Affiliation Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  ⨯
• Wenhui Li ,

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: wenhuili64@yeah.net (WL); hmfy81@126.com (MH)

  Affiliation Department of Oncology, The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

  ⨯
• Meifang Huang

  Roles Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: wenhuili64@yeah.net (WL); hmfy81@126.com (MH)

  Affiliation Department of Oncology, The First People’s Hospital of Qujing/The Qujing Affiliated Hospital of Kunming Medical University, Qujing, Yunnan, China

  https://orcid.org/0000-0002-4230-493X

  ⨯