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Open Access
Peer-reviewed
Research Article
Factors associated with low health-related quality of life in persons with multiple sclerosis: A quantile-based segmentation approach
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Stefania Iaquinto,
Roles Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland
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Benjamin Victor Ineichen,
Roles Writing – review & editing
Affiliation Center for Reproducible Science (CRS), University of Zurich, Zurich, Switzerland
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Anke Salmen,
Roles Writing – review & editing
Affiliation Department of Neurology, St. Josef-Hospital Bochum, Ruhr-University Bochum, Bochum, Germany
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Jens Kuhle,
Roles Writing – review & editing
Affiliations Department of Neurology, University Hospital Basel and University of Basel, Basel, Switzerland, Neurology Clinic and Polyclinic, Departments of Head, Spine and Neuromedicine, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), Clinical Research and Biomedical Engineering, University Hospital Basel and University of Basel, Basel, Switzerland
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Pascal Benkert,
Roles Writing – review & editing
Affiliation Clinical Trial Unit, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland
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Lisa Hofer,
Roles Writing – review & editing
Affiliation Clinical Trial Unit, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland
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Pasquale Calabrese,
Roles Writing – review & editing
Affiliation Division of Cognitive and Molecular Neuroscience, Neuropsychology and Behavioral Neurology Unit, University of Basel, Basel, Switzerland
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Christian P. Kamm,
Roles Writing – review & editing
Affiliations Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, Neurocentre, Lucerne Cantonal Hospital, Lucerne, Switzerland
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Patrick Roth,
Roles Writing – review & editing
Affiliation Department of Neurology and Brain Tumor Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland
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Chiara Zecca,
Roles Writing – review & editing
Affiliations Department of Neurology, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano, EOC, Lugano, Switzerland, Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland
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Sabin Ammann,
Roles Writing – review & editing
Affiliation Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland
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Caroline Pot,
Roles Writing – review & editing
Affiliation Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
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Viktor von Wyl ,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: viktor.vonwyl@uzh.ch
Affiliations Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland
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for the Swiss Multiple Sclerosis Registry
¶Members belonging to the Swiss Multiple Sclerosis Registry are included in the Acknowledgments.
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Factors associated with low health-related quality of life in persons with multiple sclerosis: A quantile-based segmentation approach
- Stefania Iaquinto,
- Benjamin Victor Ineichen,
- Anke Salmen,
- Jens Kuhle,
- Pascal Benkert,
- Lisa Hofer,
- Pasquale Calabrese,
- Christian P. Kamm,
- Patrick Roth,
- Chiara Zecca
- Published: November 21, 2024
- https://doi.org/10.1371/journal.pone.0312486