The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins

• Xiaohui Liu ,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: xiaohui@bio.sojo-u.ac.jp (XL); shimo@kyudai.jp (YS)

  Affiliations Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka, Japan, Department of Biotechnology and Life Sciences, Faculty of Biotechnology and Life Sciences, Sojo University, Kumamoto, Japan

  https://orcid.org/0000-0003-3162-429X

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• Yutaka Matsuyama,

  Roles Data curation, Formal analysis

  Affiliation Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka, Japan

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• Makiko Sugiyama,

  Roles Data curation, Formal analysis

  Affiliation Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka, Japan

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• Keitaro Suyama,

  Roles Data curation, Methodology, Software, Validation

  Affiliations Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka, Japan, Faculty of Arts and Science, Kyushu University, Fukuoka, Japan

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• Takeru Nose,

  Roles Methodology, Validation

  Affiliations Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka, Japan, Faculty of Arts and Science, Kyushu University, Fukuoka, Japan

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• Miki Shimohigashi,

  Roles Methodology, Validation, Writing – review & editing

  Affiliations Division of Biology, Department of Earth System of Science, Faculty of Science, Fukuoka University, Fukuoka, Japan, Risk Science Research Institute, Fukuoka, Japan

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• Yasuyuki Shimohigashi

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: xiaohui@bio.sojo-u.ac.jp (XL); shimo@kyudai.jp (YS)

  Affiliations Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka, Japan, Risk Science Research Institute, Fukuoka, Japan

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