Benchmarking methods for computing local sensitivities in ordinary differential equation models at dynamic and steady states

Polina Lakrisenko; Dilan Pathirana; Daniel Weindl; Jan Hasenauer

doi:10.1371/journal.pone.0312148

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Peer-reviewed

Research Article

Benchmarking methods for computing local sensitivities in ordinary differential equation models at dynamic and steady states

Polina Lakrisenko,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliations Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany, School of Life Sciences, Technische Universität München, Freising, Germany

https://orcid.org/0000-0002-7626-8420

⨯
Dilan Pathirana,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Faculty of Mathematics and Natural Sciences, and the Life and Medical Sciences Institute (LIMES), Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯
Daniel Weindl,

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

Affiliations Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany, Faculty of Mathematics and Natural Sciences, and the Life and Medical Sciences Institute (LIMES), Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany

https://orcid.org/0000-0001-9963-6057

⨯
Jan Hasenauer

Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

* E-mail: jan.hasenauer@uni-bonn.de

Affiliations Computational Health Center, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany, Faculty of Mathematics and Natural Sciences, and the Life and Medical Sciences Institute (LIMES), Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany
⨯

Benchmarking methods for computing local sensitivities in ordinary differential equation models at dynamic and steady states

Polina Lakrisenko,
Dilan Pathirana,
Daniel Weindl,
Jan Hasenauer

Published: October 23, 2024
https://doi.org/10.1371/journal.pone.0312148

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